Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 15/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | BLVRB | P30043 | 1/20 | 0.46 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2720313 | 0.90 | XDH (0.54) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL3379631 | 0.90 | XDH (0.48) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL3381359 | 0.90 | XDH (0.60) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL2721061 | 0.88 | XDH (0.50) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL1331619 | 0.87 | XDH (0.66) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL2719649 | 0.86 | XDH (0.45) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL3385772 | 0.84 | XDH (0.46) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL16762585 | 0.77 | XDH (0.54) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL19523348 | 0.77 | XDH (0.68) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL1357815 | 0.77 | XDH (0.68) | XDHABCC4ABCB11PGRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932832-B1 | TRIARYLCARBOXYLIC ACID DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2010-12-01 | — | — | EP | claimed |