Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 14/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | BLVRB | P30043 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2720313 | 0.91 | XDH (0.54) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL3379631 | 0.89 | XDH (0.48) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL3381359 | 0.89 | XDH (0.60) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL3384040 | 0.85 | XDH (0.60) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL3386201 | 0.84 | XDH (0.58) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL2719649 | 0.83 | XDH (0.45) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL2721061 | 0.81 | XDH (0.50) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL13004635 | 0.77 | HSD17B1 (0.45) | XDHMAPTGRM5 | |
| SCHEMBL16762585 | 0.77 | XDH (0.54) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL1357815 | 0.76 | XDH (0.68) | XDHABCC4ABCB11PGRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932832-B1 | TRIARYLCARBOXYLIC ACID DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2010-12-01 | — | — | EP | claimed |