SCHEMBL33864

SCHEMBL33864

Nc1ccc(Nc2ccc(N)cc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.78
ALDH1A1 P00352 6/20 0.78
L3MBTL1 Q9Y468 3/20 0.78
CYP3A4 P08684 3/20 0.78
ALOX12 P18054 2/20 0.78
CYP1A2 P05177 1/20 0.78
CYP2C9 P11712 1/20 0.78
CYP2C19 P33261 1/20 0.78
HTT P42858 1/20 0.78
RAD52 P43351 1/20 0.70
NR4A1 P22736 1/20 0.64
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
HSD17B10 Q99714 4/20 0.56
ALOX15 P16050 4/20 0.56
TP53 P04637 2/20 0.56
KDM4E B2RXH2 2/20 0.56
APP P05067 1/20 0.56
HPGD P15428 1/20 0.56
SNCA P37840 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12747008 1.00 MAPT (0.78) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL5438258 1.00 MAPT (0.78) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL5428343 1.00 MAPT (0.78) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL18289620 1.00 MAPT (0.78) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL1459001 0.97 MAPT (0.74) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL8440919 0.97 MAPT (0.74) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL9518383 0.91 MAPT (0.67) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL6301188 0.91 MAPT (0.67) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL30463 0.91 MAPT (0.67) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL351125 0.91 MAPT (0.67) MAPTALDH1A1L3MBTL1CYP3A4ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7699 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080397-A Enzyme reactor based on amorphous Porous Organic Polymers (POPs), preparation method and application 2026-05-26 CN claimed
CN-122080510-A Polymer sealing material for PU valve and preparation method thereof 2026-05-26 CN claimed
CN-122036516-A Synthesis process of 4,4' -diaminodiphenylamine 河北科技大学 2026-05-15 CN claimed
CN-120040699-A Covalent organic framework material and preparation method and application thereof 贵州师范学院 2025-05-27 CN claimed
CN-120037797-A Azos polymer mixed matrix membrane and preparation method and application thereof 南京工业大学 2025-05-27 CN claimed
CN-119972026-A Nitrous oxide trapping and separating adsorbent and preparation method and application thereof 中国石油大学(北京) 2025-05-13 CN claimed
CN-119711052-A Polyimide fiber membrane for radiation refrigeration and preparation method and application thereof 中国地质大学(北京) 2025-03-28 CN claimed
CN-119684717-A Medium-voltage cable shielding layer rubber compound and preparation method thereof 无锡易北河塑胶科技有限公司 2025-03-25 CN claimed
CN-119286539-B Liquid crystal aligning agent and method for preparing high-hardness polyimide liquid crystal alignment film by using same 山东齐氟新材料有限公司 2025-03-21 CN claimed
CN-119463176-A Black polyimide film and preparation method and application thereof 华东理工大学 2025-02-18 CN claimed
US-4528336-A Method for preventing polymer scale deposition in polymerization of ethylenically unsaturated monomers SHIN-ETSU CHEMICAL CO., LTD. (JP) 1985-07-09 US claimed
EP-0146350-A2 Hair treatment composition UNILEVER PLC (GB) 1985-06-26 EP claimed
EP-0134500-A2 Polymeric dye E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-03-20 EP claimed
US-4501876-A FROM AN AROMATIC DIAMINE AND A DIKETONE OR DIALDEHYDE IN STRONG PROTIC ACID; OPTICAL RECORDING/- E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-02-26 US claimed
US-4402700-A CONDITIONING CLAIROL INCORPORATED (US) 1983-09-06 US claimed
EP-0062230-A2 Method for preventing polymer scale deposition in the polymerization of ethylenically unsaturated monomers Shin-Etsu Chemical Co., Ltd. (JP) 1982-10-13 EP claimed
US-4268264-A ORTHO PRECURSORS SELECTED FROM AROMATIC DIAMINES, AMINOPHENOL, DIPHENOL, AND PHENYLENEDIAMINE L'OREAL (FR) 1981-05-19 US claimed
US-4171952-A 1,5-DIHYDROXYNAPHTHALENE, 4,4'-DIAMINODIPHENYLAMINE, P-AMINODIPHENYLAMINE, MODIFIER, COUPLER, BASE SYNTEX (U.S.A.) INC. (US) 1979-10-23 US claimed
US-4119399-A AQUEOUS, ALKALINE CLAIROL INCORPORATED (US) 1978-10-10 US claimed
US-3970423-A PHENYLENEDIAMINE DERIVATIVES CLAIROL INCORPORATED (US) 1976-07-20 US claimed