SCHEMBL5428343

SCHEMBL5428343

Nc1ccc(Nc2ccc(Nc3ccc(N)cc3)cc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.78
ALDH1A1 P00352 6/20 0.78
L3MBTL1 Q9Y468 3/20 0.78
CYP3A4 P08684 3/20 0.78
ALOX12 P18054 2/20 0.78
CYP1A2 P05177 1/20 0.78
CYP2C9 P11712 1/20 0.78
CYP2C19 P33261 1/20 0.78
HTT P42858 1/20 0.78
RAD52 P43351 1/20 0.70
NR4A1 P22736 1/20 0.64
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
HSD17B10 Q99714 4/20 0.56
ALOX15 P16050 4/20 0.56
TP53 P04637 2/20 0.56
KDM4E B2RXH2 2/20 0.56
APP P05067 1/20 0.56
HPGD P15428 1/20 0.56
SNCA P37840 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12747008 1.00 MAPT (0.78) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL5438258 1.00 MAPT (0.78) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL33864 1.00 MAPT (0.78) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL18289620 1.00 MAPT (0.78) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL1459001 0.97 MAPT (0.74) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL8440919 0.97 MAPT (0.74) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL9518383 0.91 MAPT (0.67) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL6301188 0.91 MAPT (0.67) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL30463 0.91 MAPT (0.67) MAPTALDH1A1L3MBTL1CYP3A4ALOX12
SCHEMBL351125 0.91 MAPT (0.67) MAPTALDH1A1L3MBTL1CYP3A4ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260097143-A1 STERILIZATION INDICATOR SENSOR WITH A STERILANT-RESPONSIVE SWITCH SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-04-09 US claimed
EP-4721152-A2 ORGANIC THIN FILM COATINGS FOR BATTERY MATERIALS Coreshell Technologies, Inc. (US) 2026-04-08 EP claimed
US-20250272550-A1 MEMRISTIVE SELF-LEARNING SPIKING FEEDBACK LOOPS-BASED NEURAL NETWORKS WITH SPIKE-TIMING-DEPENDENT PLASTICITY (STDP) B-RAIN ARK FZ-LLC (AE) 2025-08-28 US claimed
WO-2024249841-A2 ORGANIC THIN FILM COATINGS FOR BATTERY MATERIALS CORESHELL TECHNOLOGIES, INC. (US) 2024-12-05 WO claimed
WO-2024151279-A1 CONTINUOUS SKIN-ACETONE DETECTING MATERIAL OHIO STATE INNOVATION FOUNDATION (US) 2024-07-18 WO claimed
US-11705571-B2 Foil-based redox flow battery KOCHERGINSKY NIKOLAI M (US) 2023-07-18 US claimed
US-11577212-B2 Stimuli-responsive micro-reservoirs for release of encapsulants SAS Nanotechnologies Inc. (US) 2023-02-14 US claimed
US-20220184262-A1 STERILIZATION INDICATOR SENSOR WITH A STERILANT-RESPONSIVE SWITCH SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2022-06-16 US claimed
US-20260131038-A1 TEST DEVICE, STERILIZATION MONITORING SYSTEM AND METHOD SOLVENTUM INTELLECTUAL PROPERTIES CO (US) 2026-05-14 US disclosed
CN-122029478-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2026-05-12 CN disclosed
US-20260124332-A1 TEST DEVICE, STERILIZATION MONITORING SYSTEM AND METHOD SOLVENTUM INTELLECTUAL PROPERTIES CO (US) 2026-05-07 US disclosed
US-20260097143-A1 STERILIZATION INDICATOR SENSOR WITH A STERILANT-RESPONSIVE SWITCH SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-04-09 US disclosed
EP-4721152-A2 ORGANIC THIN FILM COATINGS FOR BATTERY MATERIALS Coreshell Technologies, Inc. (US) 2026-04-08 EP disclosed
US-12569679-B2 Treatment delivery system WearOptimo Pty Ltd (AU) 2026-03-10 US disclosed
US-20090236571-A1 STABLE, WATER-SOLUBLE NEAR INFRARED DYES EPOLIN, INC. 2009-09-24 US disclosed
US-20070187672-A1 Charge-transporting varnish and organic electro-luminescent devices made by using the same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-08-16 US disclosed
US-6518394-B2 Polyaniline, oxidation or electrochemical, aromatic amine initiator which reacts and becomes part of the polymer chain DREXEL UNIVERSITY 2003-02-11 US disclosed
US-20010037947-A1 End-functionalized aniline-based oligomers, corrosion-resistant copolymers and methods of making the same WEI YEN (US) 2001-11-08 US disclosed
US-20010034421-A1 End-functionalized aniline-based oligomers, corrosion-resistant copolymers and methods of making the same WEI YEN (US) 2001-10-25 US disclosed
US-6239251-B1 FORMING IMINE END GROUPS BY REACTION WITH AN ALDEHYDE DREXEL UNIVERSITY 2001-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124332-A1 TEST DEVICE, STERILIZATION MONITORING SYSTEM AND METHOD TES, STS, ZP1 MAPT 4419/4885ALDH1A1 1754/4885L3MBTL1 2025/4885
US-20260131038-A1 TEST DEVICE, STERILIZATION MONITORING SYSTEM AND METHOD TES, STS, SEM1 MAPT 4040/4885ALDH1A1 1085/4885L3MBTL1 1872/4885
US-20260097143-A1 STERILIZATION INDICATOR SENSOR WITH A STERILANT-RESPONSIVE SWITCH STS, ANO2, TAS2R19 MAPT 4341/4885ALDH1A1 299/4885L3MBTL1 2834/4885
US-20090236571-A1 STABLE, WATER-SOLUBLE NEAR INFRARED DYES ITK, THEM6, TDO2 MAPT 458/4885ALDH1A1 1474/4885L3MBTL1 3933/4885
US-20010037947-A1 End-functionalized aniline-based oligomers, corrosion-resistant copolymers and methods of making the same MAOA, OGG1, AAAS MAPT 2052/4885ALDH1A1 1045/4885L3MBTL1 2869/4885
US-11577212-B2 Stimuli-responsive micro-reservoirs for release of encapsulants ORAI1, CD44, VAPA MAPT 3648/4885ALDH1A1 1535/4885L3MBTL1 4627/4885
US-20010034421-A1 End-functionalized aniline-based oligomers, corrosion-resistant copolymers and methods of making the same MAOA, OGG1, AAAS MAPT 2052/4885ALDH1A1 1045/4885L3MBTL1 2869/4885
US-12569679-B2 Treatment delivery system PIEZO1, DSG1, KRT18 MAPT 910/4885ALDH1A1 4444/4885L3MBTL1 3465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.