Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 13/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.41 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386397 | 1.00 | REN (0.43) | RENPSMB5PSMB1PSMB8PSMB9 | |
| SCHEMBL3384240 | 0.84 | SYK (0.45) | RENPSMB5PSMB1PSMB8PSMB9 | |
| SCHEMBL3384235 | 0.84 | SYK (0.45) | RENPSMB5PSMB1PSMB8PSMB9 | |
| SCHEMBL3384237 | 0.84 | SYK (0.45) | RENPSMB5PSMB1PSMB8PSMB9 | |
| SCHEMBL3383789 | 0.84 | CTSS (0.40) | RENBCHEACHECTSS | |
| SCHEMBL3382121 | 0.82 | MEN1 (0.47) | RENPSMB5PSMB1PSMB8PSMB9 | |
| SCHEMBL3382125 | 0.82 | MEN1 (0.47) | RENPSMB5PSMB1PSMB8PSMB9 | |
| SCHEMBL3382127 | 0.82 | MEN1 (0.47) | RENPSMB5PSMB1PSMB8PSMB9 | |
| SCHEMBL5125970 | 0.81 | PSMB5 (0.39) | RENPSMB5PSMB1PSMB8PSMB9 | |
| SCHEMBL3379680 | 0.81 | MEN1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765850-B1 | SUBSTITUTED PROPANE PHOSPHINIC ACID DERIVATIVES | AVENTIS PHARMA INC (US) | 2010-12-01 | — | — | EP | disclosed |