Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 15/20 | 0.52 |
| ▸ | KDR | P35968 | 14/20 | 0.52 |
| ▸ | IDH2 | P48735 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27705851 | 0.92 | MEN1 (0.50) | FGFR3KDR | |
| SCHEMBL27705887 | 0.90 | FGFR3 (0.54) | FGFR3KDR | |
| SCHEMBL3190830 | 0.86 | KDR (0.66) | FGFR3KDR | |
| SCHEMBL3186936 | 0.83 | FGFR3 (0.56) | FGFR3KDR | |
| SCHEMBL3189323 | 0.83 | KDR (0.59) | FGFR3KDR | |
| SCHEMBL3386132 | 0.81 | KDR (0.55) | FGFR3KDR | |
| SCHEMBL3323290 | 0.81 | FGFR3 (0.77) | FGFR3KDR | |
| SCHEMBL3383389 | 0.80 | NPC1 (0.64) | FGFR3KDR | |
| SCHEMBL3417464 | 0.80 | FGFR3 (0.51) | FGFR3KDR | |
| SCHEMBL3383649 | 0.80 | KDR (0.55) | FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128461-B | Imidazo (1, 2-a) pyridine compounds as VEGF-R2 inhibitors | LILLY CO ELI | 2010-12-22 | — | — | CN | disclosed |
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |
| CN-101128461-A | Imidazo (1, 2-a) pyridine compounds as VEGF-R2 inhibitors | LILLY CO ELI (US) | 2008-02-20 | — | — | CN | disclosed |