SCHEMBL33865

SCHEMBL33865

NNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.71

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.71
MEN1 O00255 1/20 0.71
ABL1 P00519 1/20 0.71
LMNA P02545 1/20 0.71
PKM P14618 1/20 0.71
IDE P14735 1/20 0.71
MAPK1 P28482 1/20 0.71
KMT2A Q03164 1/20 0.71
RIN1 Q13671 1/20 0.71
L3MBTL1 Q9Y468 1/20 0.71
CA12 O43570 6/20 0.63
CA1 P00915 6/20 0.63
CA2 P00918 6/20 0.63
CA9 Q16790 6/20 0.63
HLCS P50747 6/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL565406 1.00 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
SCHEMBL5585656 1.00 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
SCHEMBL12424056 1.00 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
SCHEMBL19514780 1.00 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
SCHEMBL5585660 1.00 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
SCHEMBL10140211 1.00 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
SCHEMBL14812382 0.99 TDP1 (0.70) TDP1MEN1ABL1LMNAPKM
Hydrazine SCHEMBL28140320 0.99 TDP1 (0.70) TDP1MEN1ABL1LMNAPKM
SCHEMBL23863708 0.96 TDP1 (0.65) TDP1MEN1ABL1LMNAPKM
SCHEMBL1024507 0.94 HLCS (0.72) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3148 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122084901-A Method for diagnosing prostate cancer by using exosome surface protein spectrum 2026-05-26 CN claimed
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US claimed
WO-2026107515-A1 INCRETIN HORMONE COMPOSITIONS AND METHODS USING SAME DIASOME PHARMACEUTICALS, INC. (US) 2026-05-21 WO claimed
US-20260124139-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL DIASOME PHARMACEUTICALS INC (US) 2026-05-07 US claimed
EP-4703373-A1 POLYPEPTIDES AND RELATED SUBSTANCES AGAINST HAIR LOSS AND DERMATITIS, AND USES THEREOF Shenzhen Institutes of Advanced Technology (CN) 2026-03-04 EP claimed
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2025-09-18 US claimed
US-12332249-B1 Biomolecule detection method using diffusion ordered spectroscopy KUWAIT UNIVERSITY (KW) 2025-06-17 US claimed
EP-4520766-A1 OVARY-TARGETING POLYPEPTIDE, AND DERIVATIVE AND USE THEREOF Shenzhen Institute of Advanced Technology Chinese Academy of Sciences (CN) 2025-03-12 EP claimed
US-20250057911-A1 OVARY-TARGETING POLYPEPTIDE, AND DERIVATIVE AND THE USE THEREOF SHENZHEN INSTITUTES OF ADVANCEDTECHNOLOGY CHINESE ACADEMY OF SCIENCES (CN) 2025-02-20 US claimed
WO-2025000474-A1 POLYPEPTIDE FOR COUNTERACTING ALOPECIA AND DERMATITIS, AND RELATED SUBSTANCE AND USE THEREOF 深圳先进技术研究院 2025-01-02 WO claimed
EP-0961833-A1 HUMAN PLASMA HYALURONIDASE The Regents of the University of California (US) 1999-12-08 EP claimed
EP-0837869-A2 METHOD FOR PRODUCING SYNTHETIC N-LINKED GLYCOCONJUGATES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 1998-04-29 EP claimed
WO-1998016655-A1 HUMAN PLASMA HYALURONIDASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-04-23 WO claimed
US-5668272-A Method for producing synthetic N-linked glycoconjugates NATIONAL RESEARCH COUNCIL OF CANADA (CA) 1997-09-16 US claimed
WO-1997002277-A2 METHOD FOR PRODUCING SYNTHETIC N-LINKED GLYCOCONJUGATES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 1997-01-23 WO claimed
EP-0088542-B1 SKIN TREATMENT COMPOSITION UNILEVER N.V. (NL) 1988-05-11 EP claimed
EP-0256117-A1 LATEX AGGLUTINATION USING AVIDIN/BIOTIN SYSTEM MICROBIOLOGICAL ASSOCIATES, INC. (US) 1988-02-24 EP claimed
WO-1987004794-A1 LATEX AGGLUTINATION USING AVIDIN/BIOTIN SYSTEM MICROBIOLOGICAL ASSOCIATES, INC. (US) 1987-08-13 WO claimed
US-4529587-A Using biotin antagonist LEVER BROTHERS COMPANY (US) 1985-07-16 US claimed
EP-0088542-A2 Skin treatment composition UNILEVER N.V. (NL) 1983-09-14 EP claimed