Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HLCS | P50747 | 5/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ABL1 | P00519 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | IDE | P14735 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 6/20 | 0.58 |
| ▸ | CA1 | P00915 | 6/20 | 0.58 |
| ▸ | CA2 | P00918 | 6/20 | 0.58 |
| ▸ | CA9 | Q16790 | 6/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL912901 | 0.97 | HLCS (0.67) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL1075131 | 0.96 | HLCS (0.66) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL10140211 | 0.94 | TDP1 (0.71) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL33865 | 0.94 | TDP1 (0.71) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL12424056 | 0.94 | TDP1 (0.71) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL5585660 | 0.94 | TDP1 (0.71) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL5585656 | 0.94 | TDP1 (0.71) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL565406 | 0.94 | TDP1 (0.71) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL19514780 | 0.94 | TDP1 (0.71) | HLCSTDP1MEN1ABL1LMNA | |
| Biotin SCHEMBL27481190 | 0.93 | TDP1 (0.72) | HLCSTDP1MEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183060-B2 | comprises biotin covalently attached to a polymer that has monosaccharide or amino acid as a constituent monomer covalently attached to a luminescent substance (cyanoisoindoles, luminols, and acridinium esters); detecting a target substance at high sensitivity | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2012-05-22 | — | — | US | disclosed |
| EP-1437594-B1 | LUMINESCENT POLYMER AND USE THEREOF IN BIOASSAY | SEKISUI MEDICAL CO LTD (JP) | 2011-01-12 | — | — | EP | disclosed |
| US-20050019573-A1 | comprises biotin covalently attached to a polymer that has monosaccharide or amino acid as a constituent monomer covalently attached to a luminescent substance (cyanoisoindoles, luminols, and acridinium esters); detecting a target substance at high sensitivity | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2005-01-27 | — | — | US | disclosed |
| EP-1437594-A1 | LUMINESCENT POLYMER AND USE THEREOF IN BIOASSAY | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2004-07-14 | — | — | EP | disclosed |