Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386085 | 0.84 | PDE10A (0.42) | PDE10AMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL3382640 | 0.75 | ALDH1A1 (0.61) | ALDH1A1LMNANPSR1CYP1A2CYP3A4 | |
| SCHEMBL20340591 | 0.74 | GAA (0.60) | PDE10AHPGDMAPTALDH1A1MAPK1 | |
| SCHEMBL3541348 | 0.69 | ALDH1A1 (0.64) | ALDH1A1LMNANPSR1CYP1A2CYP3A4 | |
| SCHEMBL27930198 | 0.68 | PDE10A (0.59) | PDE10AMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL4591181 | 0.67 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL5780925 | 0.67 | PDE10A (0.43) | PDE10AMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL18177308 | 0.65 | GAA (0.57) | PDE10AMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL22119735 | 0.65 | PDE10A (0.59) | PDE10AMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL30033520 | 0.65 | PDE10A (0.59) | PDE10AMEN1KMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984366-B1 | 3, 9-DIAZABICYCLO Ý3.3. 1¨NONANE DERIVATIVES AND THEIR USE AS MONOAMINE?NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH AS (DK) | 2010-12-15 | — | — | EP | claimed |