SCHEMBL33866

SCHEMBL33866

COCc1cc(N)ccc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.56
ACHE P22303 3/20 0.55
PDE10A Q9Y233 1/20 0.47
PRKCE Q02156 3/20 0.46
MYLK Q15746 2/20 0.46
MAPT P10636 2/20 0.46
MEN1 O00255 2/20 0.46
ALDH1A1 P00352 2/20 0.46
RECQL P46063 2/20 0.46
KMT2A Q03164 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
PRKCG P05129 1/20 0.46
PRKCA P17252 1/20 0.46
APEX1 P27695 1/20 0.46
TSHR P16473 2/20 0.42
CASP1 P29466 2/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
GAA P10253 2/20 0.42
HTT P42858 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3341914 0.98 ACHE (0.58) PRKCIACHEPDE10APRKCEMYLK
SCHEMBL6152960 0.93 PRKCI (0.50) PRKCIACHEPDE10APRKCEMYLK
SCHEMBL8435914 0.86 PRKCI (0.44) PRKCIACHEPDE10APRKCEMYLK
SCHEMBL7799253 0.83 PRKCI (0.55) PRKCIACHEPDE10AMAPTMEN1
SCHEMBL1887779 0.81 MAPT (0.50) PRKCIACHEPRKCEMYLKMAPT
SCHEMBL6712520 0.81 PRKCE (0.50) PRKCEMYLKMAPTMEN1ALDH1A1
SCHEMBL8140506 0.81 PRKCI (0.53) PRKCIACHEPDE10AMAPTMEN1
SCHEMBL7761828 0.81 PRKCI (0.58) PRKCIACHEPDE10AMAPTMEN1
SCHEMBL8391922 0.79 PRKCI (0.51) PRKCIACHEPDE10AMEN1ALDH1A1
Hydrochloric Acid SCHEMBL9758701 0.79 ACHE (0.59) PRKCIACHEPDE10AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5651 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11555017-B2 Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres L'OREAL (FR) 2023-01-17 US claimed
US-20200392088-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2020-12-17 US claimed
US-10639257-B2 Composition for colouring keratin fibres BEAUTY & BUSINESS S.P.A. (IT) 2020-05-05 US claimed
EP-3464247-B1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES OREAL (FR) 2020-03-11 EP claimed
US-20190117541-A1 COMPOSITION FOR COLOURING KERATIN FIBRES BEAUTY & BUSINESS S.P.A. (IT) 2019-04-25 US claimed
EP-3464247-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'Oréal (FR) 2019-04-10 EP claimed
US-9993413-B2 Keratin fibre dyeing composition BEAUTY & BUSINESS S.P.A. (IT) 2018-06-12 US claimed
WO-2017202884-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2017-11-30 WO claimed
US-20170258695-A1 KERATIN FIBRE DYEING COMPOSITION BEAUTY & BUSINESS S.P.A. (IT) 2017-09-14 US claimed
EP-3096735-A1 GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME Combe International Ltd. (US) 2016-11-30 EP claimed
EP-0460128-A1 AGENT AND PROCESS FOR THE OXIDATIVE DYEING OF HAIR. WELLA AG (DE) 1991-12-11 EP claimed
EP-0459900-A1 Process for dyeing of keratinic fibres with 2,4-diamino-1,3-dimethoxybenzene in an acid medium and composition using this process L'OREAL (FR) 1991-12-04 EP claimed
US-5053052-A Washfast, lightfast oxidation color dyes L'OREAL (FR) 1991-10-01 US claimed
EP-0446132-A1 Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions L'OREAL (FR) 1991-09-11 EP claimed
WO-1991009587-A1 AGENT AND PROCESS FOR THE OXIDATIVE DYEING OF HAIR WELLA AKTIENGESELLSCHAFT (DE) 1991-07-11 WO claimed
CN-1051727-A Use 6-or 7-hydroxy indoxyl derivative as chromogenic reagent, contain the composition of this derivative and the staining of carrying out with said composition OREAL (FR) 1991-05-29 CN claimed
EP-0428441-A2 Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same L'OREAL (FR) 1991-05-22 EP claimed
EP-0428442-A1 Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same L'OREAL (FR) 1991-05-22 EP claimed
US-4997451-A Developers WELLA AKTIENGESELLSCHAFT (DE) 1991-03-05 US claimed
EP-0395837-A1 Oxidation hair dyes based on 4-aminophenol derivatives as well as new 4-aminophenol derivatives Wella Aktiengesellschaft (DE) 1990-11-07 EP claimed