Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761828 | 0.88 | PRKCI (0.58) | PRKCIACHECA1CA2PDE10A | |
| Hydrochloric Acid SCHEMBL9758701 | 0.87 | ACHE (0.59) | PRKCIACHECA1CA2PDE10A | |
| SCHEMBL8034678 | 0.87 | PRKCI (0.47) | PRKCIACHECA1CA2PDE10A | |
| SCHEMBL8393250 | 0.85 | PRKCI (0.54) | PRKCIACHECA1CA2PDE10A | |
| Water SCHEMBL9445096 | 0.85 | PRKCI (0.46) | PRKCIACHECA1CA2PDE10A | |
| Hydrochloric Acid SCHEMBL9757869 | 0.85 | ACHE (0.49) | PRKCIACHECA1CA2PDE10A | |
| SCHEMBL8393572 | 0.84 | PRKCI (0.45) | PRKCIACHECA1CA2PDE10A | |
| Hydrochloric Acid SCHEMBL9523233 | 0.84 | ACHE (0.56) | PRKCIACHECA1CA2PDE10A | |
| SCHEMBL33866 | 0.83 | PRKCI (0.56) | PRKCIACHECA1CA2PDE10A | |
| Hydrochloric Acid SCHEMBL3341914 | 0.82 | ACHE (0.58) | PRKCIACHECA1CA2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010004779-A1 | Novel p-aminophenol derivatives and the use thereof | ROSE DAVID (DE) | 2001-06-28 | — | — | US | claimed |
| EP-1044185-A2 | NEW DERIVATIVES OF P-AMINOPHENOL AND THEIR USE | Henkel Kommanditgesellschaft auf Aktien (DE) | 2000-10-18 | — | — | EP | claimed |
| WO-1999031054-A2 | NOVEL P-AMINOPHENOL DERIVATIVES AND THE USE THEREOF | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-06-24 | — | — | WO | claimed |
| US-4137080-A | POLYFUNCTIONAL COUPLER AND DEVELOPER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1979-01-30 | — | — | US | claimed |
| US-20010004779-A1 | Novel p-aminophenol derivatives and the use thereof | ROSE DAVID (DE) | 2001-06-28 | — | — | US | disclosed |
| EP-1044185-A2 | NEW DERIVATIVES OF P-AMINOPHENOL AND THEIR USE | Henkel Kommanditgesellschaft auf Aktien (DE) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999031054-A2 | NOVEL P-AMINOPHENOL DERIVATIVES AND THE USE THEREOF | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-06-24 | — | — | WO | disclosed |
| US-4137080-A | POLYFUNCTIONAL COUPLER AND DEVELOPER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1979-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010004779-A1 | Novel p-aminophenol derivatives and the use thereof | KRT18, S100P, CKAP4 | PRKCI 712/4885ACHE 3309/4885CA1 4005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.