Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 19/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387164 | 1.00 | CCR5 (0.54) | CCR5KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL3391814 | 0.99 | CCR5 (0.53) | CCR5KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL3391810 | 0.99 | CCR5 (0.53) | CCR5KDM1AMAOB | |
| SCHEMBL3391654 | 0.97 | CCR5 (0.49) | CCR5KDM1AMAOB | |
| SCHEMBL3391658 | 0.97 | CCR5 (0.49) | CCR5KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL3394503 | 0.96 | CCR5 (0.48) | CCR5KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL3394502 | 0.96 | CCR5 (0.48) | CCR5KDM1AMAOB | |
| SCHEMBL3394998 | 0.93 | CCR5 (0.46) | CCR5KDM1AMAOB | |
| SCHEMBL3394993 | 0.93 | CCR5 (0.46) | CCR5KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL3395052 | 0.93 | CCR5 (0.45) | CCR5KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709642-B2 | Spirohydantoin compounds and methods for the modulation of chemokine receptor activity | VIROCHEM PHARMA, INC. (CA) | 2010-05-04 | — | — | US | claimed |