Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 17/20 | 0.51 |
| ▸ | EGFR | P00533 | 9/20 | 0.51 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.51 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.51 |
| ▸ | FECH | P22830 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.44 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387665 | 1.00 | ERBB2 (0.51) | ERBB2EGFRERBB3ERBB4FECH | |
| SCHEMBL2747902 | 0.88 | ERBB2 (0.65) | ERBB2EGFRERBB3ERBB4FECH | |
| SCHEMBL2747892 | 0.88 | ERBB2 (0.65) | ERBB2EGFRERBB3ERBB4FECH | |
| SCHEMBL2747282 | 0.80 | ERBB2 (0.65) | ERBB2EGFRERBB3ERBB4FECH | |
| SCHEMBL2747289 | 0.80 | ERBB2 (0.65) | ERBB2EGFRERBB3ERBB4FECH | |
| SCHEMBL2749945 | 0.80 | ERBB2 (0.63) | ERBB2EGFRERBB3ERBB4FECH | |
| SCHEMBL2749960 | 0.80 | ERBB2 (0.63) | ERBB2EGFRERBB3ERBB4FECH | |
| SCHEMBL2748942 | 0.77 | ERBB2 (0.74) | ERBB2EGFRERBB3ERBB4FECH | |
| SCHEMBL2748940 | 0.77 | ERBB2 (0.74) | ERBB2EGFRERBB3ERBB4FECH | |
| SCHEMBL6017285 | 0.76 | ERBB2 (0.51) | ERBB2EGFRERBB3ERBB4FECH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036910-A1 | HEART PROTECTION BY ADMINISTERING AN AMP-ACTIVATED PROTEIN KINASE ACTIVATOR | OHTA YOSHIKAZU (JP) | 2010-04-01 | — | — | WO | disclosed |