SCHEMBL3387665 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	ERBB2	P04626	17/20	0.51

▸	EGFR	P00533	9/20	0.51

▸	ERBB3	P21860	1/20	0.51

▸	ERBB4	Q15303	1/20	0.51

▸	FECH	P22830	1/20	0.44

▸	CDK8	P49336	1/20	0.44

▸	MAP2K5	Q13163	1/20	0.44

▸	CDK19	Q9BWU1	1/20	0.44

▸	MKNK2	Q9HBH9	1/20	0.44

▸	KCNH2	Q12809	3/20	0.41

▸	HDAC1	Q13547	2/20	0.37

▸	HDAC6	Q9UBN7	2/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3387660	1.00	ERBB2 (0.51)	ERBB2EGFRERBB3ERBB4FECH
SCHEMBL2747902	0.88	ERBB2 (0.65)	ERBB2EGFRERBB3ERBB4FECH
SCHEMBL2747892	0.88	ERBB2 (0.65)	ERBB2EGFRERBB3ERBB4FECH
SCHEMBL2747282	0.80	ERBB2 (0.65)	ERBB2EGFRERBB3ERBB4FECH
SCHEMBL2747289	0.80	ERBB2 (0.65)	ERBB2EGFRERBB3ERBB4FECH
SCHEMBL2749945	0.80	ERBB2 (0.63)	ERBB2EGFRERBB3ERBB4FECH
SCHEMBL2749960	0.80	ERBB2 (0.63)	ERBB2EGFRERBB3ERBB4FECH
SCHEMBL2748942	0.77	ERBB2 (0.74)	ERBB2EGFRERBB3ERBB4FECH
SCHEMBL2748940	0.77	ERBB2 (0.74)	ERBB2EGFRERBB3ERBB4FECH
SCHEMBL6017285	0.76	ERBB2 (0.51)	ERBB2EGFRERBB3ERBB4FECH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010036910-A1	HEART PROTECTION BY ADMINISTERING AN AMP-ACTIVATED PROTEIN KINASE ACTIVATOR	OHTA YOSHIKAZU (JP)	2010-04-01	—	—	WO	disclosed