Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387702 | 1.00 | TP53 (0.33) | TP53TSHRHSD17B10MGAMGAA | |
| SCHEMBL3391782 | 1.00 | TP53 (0.33) | TP53TSHRHSD17B10MGAMGAA | |
| SCHEMBL28105582 | 0.83 | G6PD (0.30) | — | |
| SCHEMBL5252146 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL28882399 | 0.79 | — | — | |
| SCHEMBL6402098 | 0.79 | TP53 (0.33) | TP53TSHRHSD17B10MGAMGAA | |
| SCHEMBL3301908 | 0.77 | — | — | |
| SCHEMBL27456563 | 0.76 | TDP1 (0.32) | — | |
| SCHEMBL28709381 | 0.76 | TP53 (0.32) | TP53TSHR | |
| SCHEMBL14690734 | 0.72 | GRIK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931629-B1 | SYNTHESIS OF RENIN INHIBITORS INVOLVING A CYCLOADDITION REACTION | NOVARTIS AG (CH) | 2010-12-22 | — | — | EP | disclosed |
| EP-1931629-A1 | SYTHESIS OF RENIN INHIBITORS INVOLVING A CYCLOADDITION REACTION | Novartis AG (CH) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007039183-A1 | SYTHESIS OF RENIN INHIBITORS INVOLVING A CYCLOADDITION REACTION | NOVARTIS AG (CH) | 2007-04-12 | — | — | WO | disclosed |