Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418907 | 1.00 | SMN1; SMN2 (0.32) | SMN1; SMN2LTA4HPDE7A | |
| SCHEMBL19863554 | 0.93 | PDE7A (0.33) | SMN1; SMN2LTA4HPDE7A | |
| SCHEMBL21222568 | 0.76 | LTA4H (0.34) | LTA4HPDE7A | |
| SCHEMBL13377825 | 0.76 | ALDH1A1 (0.35) | LTA4HPDE7A | |
| SCHEMBL718126 | 0.76 | LTA4H (0.34) | LTA4HPDE7A | |
| SCHEMBL13722593 | 0.76 | LTA4H (0.34) | LTA4HPDE7A | |
| SCHEMBL13377829 | 0.74 | PDE7A (0.32) | LTA4HPDE7A | |
| SCHEMBL15262631 | 0.74 | — | — | |
| SCHEMBL13331607 | 0.73 | LTA4H (0.33) | LTA4HPDE7A | |
| SCHEMBL20323810 | 0.72 | LTA4H (0.34) | LTA4HPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1933835-B1 | TETRAHYDRO-PYRROLO[1,2-B]ISOTHIAZOLE 1,1-DIOXIDES AS LFA-1 INHIBITORS | NOVARTIS AG (CH) | 2010-12-08 | — | — | EP | claimed |
| WO-2022242750-A1 | PIPERAZINE DERIVATIVE AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-11-24 | — | — | WO | disclosed |
| EP-1933835-B1 | TETRAHYDRO-PYRROLO[1,2-B]ISOTHIAZOLE 1,1-DIOXIDES AS LFA-1 INHIBITORS | NOVARTIS AG (CH) | 2010-12-08 | — | — | EP | disclosed |