Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2587213 | 0.89 | LMNA (0.37) | POLBLMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL2587513 | 0.89 | RNASE1 (0.40) | POLBLMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL2580684 | 0.89 | POLB (0.36) | POLBLMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL2587599 | 0.89 | POLB (0.36) | POLBLMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL2584230 | 0.89 | POLB (0.36) | POLBLMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL2581114 | 0.87 | POLB (0.35) | POLBLMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL2583846 | 0.87 | POLB (0.35) | POLBLMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL2579327 | 0.87 | CA12 (0.36) | POLBLMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL2580798 | 0.87 | POLB (0.35) | POLBLMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL2583493 | 0.86 | TSHR (0.36) | POLBLMNATHRBSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411954-B1 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | PHARMASSET INC (US) | 2010-12-15 | — | — | EP | disclosed |