SCHEMBL338788

SCHEMBL338788

CC(=O)Nc1ccccc1Nc1ccc(Br)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.54
MAPT P10636 4/20 0.53
POLB P06746 1/20 0.53
ALDH1A1 P00352 3/20 0.53
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
LMNA P02545 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HPGD P15428 1/20 0.50
MAPK13 O15264 1/20 0.49
MAPK12 P53778 1/20 0.49
MAPK11 Q15759 1/20 0.49
MAPK14 Q16539 1/20 0.49
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
RAB9A P51151 4/20 0.47
NPC1 O15118 3/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20631546 0.85 MAPT (0.66) SIRT2MAPTPOLBALDH1A1MEN1
SCHEMBL12946106 0.85 ALDH1A1 (0.54) MAPTPOLBALDH1A1MEN1KMT2A
SCHEMBL5613323 0.84 NPC1 (0.61) SIRT2MAPTPOLBALDH1A1MEN1
SCHEMBL17077807 0.83 MAPT (0.54) SIRT2MAPTPOLBALDH1A1MEN1
SCHEMBL339128 0.82 ALDH1A1 (0.55) SIRT2MAPTPOLBALDH1A1MEN1
SCHEMBL14499598 0.82 GAA (0.57) MAPTPOLBALDH1A1MEN1KMT2A
SCHEMBL14099343 0.82 MEN1 (0.57) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL12946208 0.81 MEN1 (0.69) SIRT2MAPTMEN1KMT2ARAB9A
SCHEMBL6652892 0.80 ALDH1A1 (0.70) SIRT2MAPTPOLBALDH1A1MEN1
SCHEMBL338138 0.80 MEN1 (0.67) SIRT2MAPTPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602648-B2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO (JP) 2025-03-26 EP disclosed
CN-101503393-B Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO.,LTD. (JP) 2015-08-19 CN disclosed
EP-1602648-B1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO (JP) 2013-04-17 EP disclosed
US-8097349-B2 Nitrogen containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-01-17 US disclosed
US-7851071-B2 2-[4-(10-naphthalene-2-yl-anthracene-9-yl)-phenyl]-1-phenyl-1H-benzimidazole; elevation of luminance and of efficiency in light emission even under low driving voltage IDEMITSU KOSAN CO., LTD. (JP) 2010-12-14 US disclosed
CN-101812021-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO 2010-08-25 CN disclosed
US-20100193773-A1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD, (JP) 2010-08-05 US disclosed
EP-2174933-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
EP-2174932-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
CN-101503393-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2009-08-12 CN disclosed
US-20070138950-A1 NITROGENOUS HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-21 US disclosed
US-20070138950-A1 NITROGENOUS HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-21 US disclosed
US-20060147747-A1 2-[4-(10-naphthalene-2-yl-anthracene-9-yl)-phenyl]-1-phenyl-1H-benzimidazole; elevation of luminance and of efficiency in light emission even under low driving voltage IDEMITSU KOSAN CO., LTD. (JP) 2006-07-06 US disclosed
CN-1784388-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2006-06-07 CN disclosed
EP-1602648-A1 NITROGEN-CONTAINING HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100193773-A1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same NSD1, EED, ERG SIRT2 1049/4885MAPT 2292/4885POLB 2502/4885
US-20070138950-A1 NITROGENOUS HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME EHD1, HCN2, ODC1 SIRT2 1584/4885MAPT 3456/4885POLB 3537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.