Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.42 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439087 | 1.00 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3TSHRGRIN2D | |
| SCHEMBL24099467 | 1.00 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3TSHRGRIN2D | |
| SCHEMBL10002427 | 1.00 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3TSHRGRIN2D | |
| Hydrochloric Acid SCHEMBL26907074 | 0.98 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3TSHRGRIN2D | |
| Hydrochloric Acid SCHEMBL1440645 | 0.98 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3TSHRGRIN2D | |
| Hydrochloric Acid SCHEMBL17497471 | 0.98 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3TSHRGRIN2D | |
| Hydrochloric Acid SCHEMBL1439582 | 0.98 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3TSHRGRIN2D | |
| Hydrochloric Acid SCHEMBL31473276 | 0.98 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3TSHRGRIN2D | |
| Hydrochloric Acid SCHEMBL1439293 | 0.98 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3TSHRGRIN2D | |
| SCHEMBL22559174 | 0.86 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3TSHRGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014084312-A1 | IMIDAZOPYRIDINE COMPOUND | アステラス製薬株式会社 (JP) | 2014-06-05 | — | — | WO | disclosed |
| WO-2012002577-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | 富士フイルム株式会社 (JP) | 2012-01-05 | — | — | WO | disclosed |
| US-20090028818-A1 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC | 2009-01-29 | — | — | US | disclosed |
| WO-2009013171-A2 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090028818-A1 | Heterocyclic antiviral compounds | CCR5, CCR1, CCR2 | SLC6A2 3422/4885SLC6A4 1714/4885SLC6A3 2831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.