SCHEMBL3388583

SCHEMBL3388583

CO[Si](C)(OC)C(CCN)C1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.36
TP53 P04637 1/20 0.34
MEN1 O00255 1/20 0.33
MITF O75030 1/20 0.33
KMT2A Q03164 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SHBG P04278 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1754265 0.84 EPHX1 (0.38) EPHX1TP53MEN1MITFKMT2A
SCHEMBL6293763 0.75 EPHX1 (0.36) EPHX1TP53MEN1MITFKMT2A
SCHEMBL3724883 0.74 EPHX1 (0.35) EPHX1TP53MEN1MITFKMT2A
SCHEMBL20857002 0.72 EPHX1 (0.45) EPHX1TP53SLC6A2SLC6A4SLC6A3
SCHEMBL27318255 0.70 SHBG (0.36) EPHX1MEN1KMT2ASHBG
SCHEMBL6062805 0.66 EPHX1 (0.46) EPHX1TP53MEN1MITFKMT2A
SCHEMBL22921029 0.66 EPHX1 (0.46) EPHX1TP53MEN1MITFKMT2A
SCHEMBL26460968 0.66 EPHX1 (0.46) EPHX1TP53MEN1MITFKMT2A
SCHEMBL27368322 0.66 SHBG (0.46) EPHX1TP53KDM4ESHBG
SCHEMBL2067551 0.65 EPHX1 (0.64) EPHX1TP53MEN1KMT2ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107974108-A Reactive organic hybrid inorganic nano silica finish and its preparation and application 鳄鱼制漆(上海)有限公司 2018-05-01 CN claimed
CN-101709148-B Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof NORTH AMERICA TEMIC INC 2014-11-12 CN claimed
US-8202928-B2 Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof CONTINENTAL AUTOMOTIVE SYSTEMS, INC (US) 2012-06-19 US claimed
CN-101709148-A Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof NORTH AMERICA TEMIC INC 2010-05-19 CN claimed
CN-101705001-A A method of preparing amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof TEMIC AUTOMOTIVE NA INC 2010-05-12 CN claimed
US-20100038859-A1 METHOD OF PREPARING AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US claimed
US-20100038856-A1 AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US claimed
CN-110283497-A A method of printing the silk-screened conductive ink of accurate self limiting temperature flexible electrothermal membrane 深圳烯材科技有限公司 2019-09-27 CN disclosed
CN-110256956-A A kind of silicon rubber silane coupling agent and preparation method thereof 杭州之江新材料有限公司 2019-09-20 CN disclosed
CN-101709148-B Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof NORTH AMERICA TEMIC INC 2014-11-12 CN disclosed
US-8202928-B2 Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof CONTINENTAL AUTOMOTIVE SYSTEMS, INC (US) 2012-06-19 US disclosed
CN-101709148-A Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof NORTH AMERICA TEMIC INC 2010-05-19 CN disclosed
CN-101705001-A A method of preparing amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof TEMIC AUTOMOTIVE NA INC 2010-05-12 CN disclosed
US-20100038859-A1 METHOD OF PREPARING AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US disclosed
US-20100038856-A1 AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US disclosed