SCHEMBL6293763

SCHEMBL6293763

CC(C)O[Si](OC(C)C)(OC(C)C)C(CCN)C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.36
MEN1 O00255 1/20 0.36
MITF O75030 1/20 0.36
KMT2A Q03164 1/20 0.36
TP53 P04637 1/20 0.34
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SHBG P04278 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1754265 0.84 EPHX1 (0.38) EPHX1MEN1MITFKMT2ATP53
SCHEMBL3724883 0.81 EPHX1 (0.35) EPHX1MEN1MITFKMT2ATP53
SCHEMBL28415629 0.77 SHBG (0.41) EPHX1SHBG
SCHEMBL3388583 0.75 EPHX1 (0.36) EPHX1MEN1MITFKMT2ATP53
SCHEMBL16540317 0.71 EPHX1 (0.33) EPHX1TP53KDM4EGMNNLMNA
SCHEMBL26460968 0.70 EPHX1 (0.46) EPHX1MEN1MITFKMT2ATP53
SCHEMBL6062805 0.70 EPHX1 (0.46) EPHX1MEN1MITFKMT2ATP53
SCHEMBL22921029 0.70 EPHX1 (0.46) EPHX1MEN1MITFKMT2ATP53
SCHEMBL20857002 0.68 EPHX1 (0.45) EPHX1TP53KDM4EGMNNLMNA
SCHEMBL6289791 0.68 GABRR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6855792-B2 Cross-linking agents and thermosetting paints DEGUSSA AG (DE) 2005-02-15 US claimed
US-20020103286-A1 Cross-linking agents and thermosetting paints DEGUSSA AG (DE) 2002-08-01 US claimed
EP-1211273-A1 Crosslinker and heatcurable lacquers Degussa AG (DE) 2002-06-05 EP claimed
US-20020042471-A1 Nonaqueous, heat-curable two-component coating DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) 2002-04-11 US claimed
EP-1193278-A1 Non aqueous, heat curable, two component coating composition Degussa AG (DE) 2002-04-03 EP claimed
US-6855792-B2 Cross-linking agents and thermosetting paints DEGUSSA AG (DE) 2005-02-15 US disclosed
US-6492482-B2 WEAR AND CHEMICAL RESISTANCE DEGUSS-HUELS AKTIENGESELLSCHAFT (DE) 2002-12-10 US disclosed
US-20020103286-A1 Cross-linking agents and thermosetting paints DEGUSSA AG (DE) 2002-08-01 US disclosed
EP-1211273-A1 Crosslinker and heatcurable lacquers Degussa AG (DE) 2002-06-05 EP disclosed
US-20020042471-A1 Nonaqueous, heat-curable two-component coating DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) 2002-04-11 US disclosed
EP-1193278-A1 Non aqueous, heat curable, two component coating composition Degussa AG (DE) 2002-04-03 EP disclosed