Methanandamide

Methanandamide

SCHEMBL338871

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N[C@H](C)CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 1.00
KCNK3 O14649 1/20 1.00
ALDH1A1 P00352 1/20 1.00
THRB P10828 1/20 1.00
BLM P54132 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
SMN1; SMN2 Q16637 1/20 0.70
SLC6A5 Q9Y345 1/20 0.70
CNR1 P21554 3/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13151436 1.00 CNR2 (1.00) CNR2KCNK3ALDH1A1THRBBLM
Methanandamide SCHEMBL27775277 1.00 CNR2 (1.00) CNR2KCNK3ALDH1A1THRBBLM
Methanandamide SCHEMBL4236530 1.00 CNR2 (1.00) CNR2KCNK3ALDH1A1THRBBLM
SCHEMBL31076313 0.92 CNR2 (1.00) CNR2KCNK3ALDH1A1THRBBLM
SCHEMBL7620441 0.91 CNR2 (0.83) CNR2KCNK3ALDH1A1THRBBLM
SCHEMBL4327695 0.91 CNR2 (0.83) CNR2KCNK3ALDH1A1THRBBLM
SCHEMBL4320015 0.91 CNR2 (0.83) CNR2KCNK3ALDH1A1THRBBLM
SCHEMBL7620584 0.91 CNR2 (0.83) CNR2KCNK3ALDH1A1THRBBLM
SCHEMBL7617717 0.91 CNR2 (0.83) CNR2KCNK3ALDH1A1THRBBLM
SCHEMBL7622699 0.91 CNR2 (0.83) CNR2KCNK3ALDH1A1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 566 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102502-A1 CANNABINOID DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY UNIV JOHNS HOPKINS (US) 2026-04-16 US claimed
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
EP-4577247-A1 CANNABINOID DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY The Johns Hopkins University (US) 2025-07-02 EP claimed
US-12194020-B2 Reversing baldness through cannabinoid receptor activation POSTREL RICHARD (US) 2025-01-14 US claimed
US-20240408041-A1 COMPOSITIONS AND METHODS FOR TREATING CANNABINOID HYPEREMESIS SYNDROME HABBOUSHE JOSEPH (US) 2024-12-12 US claimed
CN-118641673-A Application of ewe fecal metabolic marker in preparation of in vitro diagnostic reagent for early pregnancy of ewe 兰州大学 2024-09-13 CN claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 WO claimed
WO-2024044776-A1 CANNABINOID DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY THE JOHNS HOPKINS UNIVERSITY (US) 2024-02-29 WO claimed
WO-2023129818-A1 GRANULAR COMPOSITION PROVIDING WATER DISPERSIBLE CANNABINOIDS AND METHODS OF MAKING THE SAME PEGASUS LABORATORIES, INC. (US) 2023-07-06 WO claimed
WO-2007047576-A1 PHARMACOLOGICAL TREATMENTS FOR SLEEP DISORDERS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2007-04-26 WO claimed
EP-1626724-A4 METHOD AND KIT FOR REGULATION OF MICROVASCULAR TONE UNIV TENNESSEE RES FOUNDATION (US) 2006-10-04 EP claimed
EP-1037673-B1 CHARGED LIPIDS AND USES FOR THE SAME IMARX PHARMACEUTICAL CORP (US) 2006-08-23 EP claimed
EP-1626724-A2 METHOD AND KIT FOR REGULATION OF MICROVASCULAR TONE University of Tennessee Research Foundation (US) 2006-02-22 EP claimed
US-20050137159-A1 Methods compositions and articles of manufacture for modulating bone growth YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM 2005-06-23 US claimed
WO-2004100867-A2 METHOD AND KIT FOR REGULATION OF MICROVASCULAR TONE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2004-11-25 WO claimed
US-20040229850-A1 Method and kit for regulation of microvascular tone UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE 2004-11-18 US claimed
US-20040127572-A1 Functional role for cannabinoids in autonomic stability during sleep CARLEY DAVID W (US) 2004-07-01 US claimed
EP-1372638-A1 FUNCTIONAL ROLE FOR CANNABINOIDS IN AUTONOMIC STABILITY DURING SLEEP THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2004-01-02 EP claimed
WO-2002080903-A1 FUNCTIONAL ROLE FOR CANNABINOIDS IN AUTONOMIC STABILITY DURING SLEEP THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2002-10-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050137159-A1 Methods compositions and articles of manufacture for modulating bone growth BMP2, CNR1, CNR2 CNR2 3/4885KCNK3 3813/4885ALDH1A1 3852/4885
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A CNR2 204/4885KCNK3 1901/4885ALDH1A1 1406/4885
US-20260102502-A1 CANNABINOID DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY CNR1, CNR2, GPR18 CNR2 2/4885KCNK3 202/4885ALDH1A1 3449/4885
US-20240408041-A1 COMPOSITIONS AND METHODS FOR TREATING CANNABINOID HYPEREMESIS SYNDROME CNR2, TRPV1, CNR1 CNR2 1/4885KCNK3 550/4885ALDH1A1 3074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.