Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.34 |
| ▸ | SIGLEC9 | Q9Y336 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424347 | 0.89 | KCNJ6 (0.36) | KCNJ6KCNJ5KCNJ3MAPK14MAPK13 | |
| SCHEMBL3388947 | 0.85 | KCNJ6 (0.50) | KCNJ6KCNJ5KCNJ3MAPK14MAPK13 | |
| SCHEMBL3392466 | 0.84 | KMT2A (0.33) | HTR1AKMT2AKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL3390273 | 0.79 | MAPK14 (0.34) | MAPK14MAPK13 | |
| SCHEMBL3389381 | 0.75 | KCNJ6 (0.40) | KCNJ6KCNJ5KCNJ3MAPK14MAPK13 | |
| SCHEMBL3388897 | 0.75 | KCNJ6 (0.41) | KCNJ6KCNJ5KCNJ3MAPK14MAPK13 | |
| SCHEMBL3388686 | 0.74 | SIGLEC9 (0.35) | KMT2ASIGLEC9LMNAMAPK14RAB9A | |
| SCHEMBL3389743 | 0.73 | PTK2B (0.35) | KMT2ASIGLEC9LMNAMAPK14MAPK13 | |
| SCHEMBL3390581 | 0.73 | P2RY12 (0.37) | KMT2AMAPK14ALDH1A1SMN1; SMN2 | |
| SCHEMBL3388827 | 0.73 | MAPK14 (0.38) | KCNJ6KCNJ5KCNJ3MAPK14MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943243-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2010-12-29 | — | — | EP | disclosed |