Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGLEC9 | Q9Y336 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392858 | 0.89 | MALT1 (0.38) | NPBWR1MCHR1MAPK14GPR119MALT1 | |
| SCHEMBL3394279 | 0.87 | MALT1 (0.37) | NPBWR1MCHR1MAPK14GPR119MALT1 | |
| SCHEMBL3388683 | 0.87 | MAPK14 (0.46) | MAPK14DDR2 | |
| SCHEMBL3170675 | 0.81 | NPY2R (0.35) | NPBWR1MCHR1MAPK14MALT1LMNA | |
| SCHEMBL3390218 | 0.79 | MAPK14 (0.51) | MAPK14DDR2 | |
| SCHEMBL3389743 | 0.77 | PTK2B (0.35) | SIGLEC9KMT2AMAPK14DDR2LMNA | |
| SCHEMBL3390581 | 0.74 | P2RY12 (0.37) | KMT2AMAPK14 | |
| SCHEMBL3392854 | 0.74 | MAPK13 (0.52) | MAPK14 | |
| SCHEMBL3170652 | 0.74 | MAPK14 (0.36) | MAPK14 | |
| SCHEMBL3388949 | 0.74 | HTR1A (0.34) | SIGLEC9KMT2AMAPK14LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943243-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2010-12-29 | — | — | EP | disclosed |