Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 2/20 | 0.44 |
| ▸ | CCND1 | P24385 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29709174 | 0.88 | NQO1 (0.53) | NQO1CHEK1MAOACDK4CCND1 | |
| SCHEMBL29352979 | 0.88 | NQO1 (0.53) | NQO1CHEK1MAOACDK4CCND1 | |
| SCHEMBL11444242 | 0.88 | NQO1 (0.53) | NQO1CHEK1MAOACDK4CCND1 | |
| SCHEMBL75410 | 0.88 | NQO1 (0.53) | NQO1CHEK1MAOACDK4CCND1 | |
| SCHEMBL1881371 | 0.86 | NQO1 (0.51) | NQO1CHEK1MAOACDK4CCND1 | |
| Hydrochloric Acid SCHEMBL28383216 | 0.86 | NQO1 (0.51) | NQO1CHEK1MAOACDK4CCND1 | |
| SCHEMBL28153683 | 0.86 | NQO1 (0.51) | NQO1CHEK1MAOACDK4CCND1 | |
| SCHEMBL11523161 | 0.86 | NQO1 (0.51) | NQO1CHEK1MAOACDK4CCND1 | |
| SCHEMBL3387676 | 0.86 | NQO1 (0.54) | NQO1CHEK1CDK4CCND1HTT | |
| SCHEMBL11150561 | 0.83 | NQO1 (0.53) | NQO1CHEK1MAOACDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513822-B1 | LYOTROPIC LIQUID CRYSTAL SYSTEM AND ANISOTROPIC FILM | NITTO DENKO CORP (JP) | 2010-12-22 | — | — | EP | disclosed |
| EP-1513822-A4 | SULFODERIVATIVES OF INDANTHRONE, LYOTROPIC LIQUID CRYSTAL SYSTEM AND ANISOTROPIC FILM ON THEIR BASE | NITTO DENKO CORP (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-6962734-B2 | Sulfoderivatives of indanthrone, lyotropic liquid crystal system and anisotropic film on their base | NITTO DENKO CORPORATION (JP) | 2005-11-08 | — | — | US | disclosed |
| US-20050129878-A1 | SULFODERIVATIVES OF INDANTHRONE, LYOTROPIC LIQUID CRYSTAL SYSTEM AND ANISOTROPIC FILM ON THEIR BASE | OPTVIA, INC. | 2005-06-16 | — | — | US | disclosed |
| EP-1513822-A2 | SULFODERIVATIVES OF INDANTHRONE, LYOTROPIC LIQUID CRYSTAL SYSTEM AND ANISOTROPIC FILM ON THEIR BASE | Optiva, Inc. (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20030232153-A1 | Sulfoderivatives of indanthrone, lyotropic liquid crystal system and anisotropic film on their base | INSOLVENCY SERVICES GROUP, INC. | 2003-12-18 | — | — | US | disclosed |
| WO-2003104242-A2 | SULFODERIVATIVES OF INDANTHRONE, LYOTROPIC LIQUID CRYSTAL SYSTEM AND ANISOTROPIC FILM ON THEIR BASE | OPTIVA, INC. (US) | 2003-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232153-A1 | Sulfoderivatives of indanthrone, lyotropic liquid crystal system and anisotropic film on their base | KCNH3, KCNH2, CCNH | NQO1 3133/4885CHEK1 1421/4885MAOA 3307/4885 |
| US-20050129878-A1 | SULFODERIVATIVES OF INDANTHRONE, LYOTROPIC LIQUID CRYSTAL SYSTEM AND ANISOTROPIC FILM ON THEIR BASE | LPAR3, IPO5, SLC6A5 | NQO1 4000/4885CHEK1 2567/4885MAOA 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.