SCHEMBL3389280

SCHEMBL3389280

C[Si](C)(C)C[Pt]C1=C(c2cc3ccccc3c3ccccc23)C=CC1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.35
CYP11B1 P15538 1/20 0.33
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP1 P29466 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TRPM4 Q8TD43 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6660633 0.73 NISCH (0.36) NISCHCYP11B1ALDH1A1HPGDTSHR
SCHEMBL3389296 0.66 CYP11B1 (0.32) NISCHCYP11B1
SCHEMBL13314087 0.62 CYP11B1 (0.52) NISCHCYP11B1ALDH1A1HPGDTSHR
SCHEMBL24505840 0.62 NISCH (0.36) NISCHCYP11B1ALDH1A1HPGDTSHR
SCHEMBL7905250 0.62 ALDH1A1 (0.60) NISCHCYP11B1ALDH1A1HPGDTSHR
SCHEMBL29637136 0.62 ALDH1A1 (0.60) NISCHCYP11B1ALDH1A1HPGDTSHR
SCHEMBL7771419 0.60 ALDH1A1 (0.40) NISCHCYP11B1ALDH1A1HPGDTSHR
SCHEMBL6660636 0.59 HPRT1 (0.41) ALDH1A1HPGDTSHRMAPK1HIF1A
SCHEMBL12627449 0.59 TRPM4 (0.42) CYP11B1ALDH1A1HPGDTSHRHIF1A
SCHEMBL12627486 0.59 TRPM4 (0.38) NISCHCYP11B1ALDH1A1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4107209-A1 PHOTOCURABLE SILICONE COMPOSITIONS AND PROCESS FOR MANUFACTURE OF RELEASE LINERS Momentive Performance Materials Inc. (US) 2022-12-28 EP disclosed
US-20210277243-A1 PHOTOCURABLE SILICONE COMPOSITIONS AND PROCESS FOR MANUFACTURE OF RELEASE LINERS MOMENTIVE PERFORMANCE MATERIALS INC. 2021-09-09 US disclosed
EP-1803728-B1 Silylalkyl platinum (IV) compounds and their production method MOMENTIVE PERFORMANCE MAT INC (US) 2010-12-15 EP disclosed
EP-1050539-B1 Irradiation-curable silicone compositions containing photo-active platinum (IV) compounds GEN ELECTRIC (US) 2007-11-14 EP disclosed
EP-1803728-A1 Silylalkyl platinum (IV) compounds and their production method General Electric Company (US) 2007-07-04 EP disclosed
EP-1050539-A2 Irradiation-curable silicone compositions containing photo-active platinum (IV) compounds GENERAL ELECTRIC COMPANY (US) 2000-11-08 EP disclosed
US-6127446-A CYCLOPENTADIENYLPLATINUM (IV) COMPOUNDS HAVING A TRISUBSTITUTED-SILYL ALIPHATIC GROUP ATTACHED TO PLATINUM BY CARBON-PLATINUM LINKAGES AS HYDROSILYLATION CATALYSTS IN IRRADIATION-CURABLE SILICONES GENERAL ELECTRIC COMPANY (US) 2000-10-03 US disclosed