SCHEMBL6660633

SCHEMBL6660633

C[Pt](C)(C)C1=C(c2cc3ccccc3c3ccccc23)C=CC1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.36
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 3/20 0.35
HIF1A Q16665 2/20 0.35
HPGD P15428 2/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TRPM4 Q8TD43 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP1B1 Q16678 1/20 0.33
HPRT1 P00492 1/20 0.31
NQO1 P15559 1/20 0.30
ALOX5 P09917 1/20 0.30
CYP1A2 P05177 2/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6660636 0.85 HPRT1 (0.41) ALDH1A1HSD17B10HIF1AHPGDTSHR
SCHEMBL6659957 0.83 NISCH (0.34) NISCHALDH1A1HSD17B10HPGDALOX5
SCHEMBL3389280 0.73 NISCH (0.35) NISCHALDH1A1HSD17B10HIF1AHPGD
SCHEMBL6656510 0.72 GSTP1 (0.33) NISCHALDH1A1HSD17B10HIF1ACASP1
Hydrochloric Acid SCHEMBL8341746 0.69 CYP1A2 (0.41) CYP1A2CYP2A6
SCHEMBL24505840 0.67 NISCH (0.36) NISCHALDH1A1HSD17B10HIF1AHPGD
SCHEMBL29637136 0.66 ALDH1A1 (0.60) NISCHALDH1A1HSD17B10HIF1AHPGD
SCHEMBL7905250 0.66 ALDH1A1 (0.60) NISCHALDH1A1HSD17B10HIF1AHPGD
Hydrochloric Acid SCHEMBL8341903 0.66 HTR6 (0.40) HPGDL3MBTL1CYP1A2CYP2A6
SCHEMBL7771419 0.65 ALDH1A1 (0.40) NISCHALDH1A1HSD17B10HIF1AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4107209-A1 PHOTOCURABLE SILICONE COMPOSITIONS AND PROCESS FOR MANUFACTURE OF RELEASE LINERS Momentive Performance Materials Inc. (US) 2022-12-28 EP disclosed
US-20210277243-A1 PHOTOCURABLE SILICONE COMPOSITIONS AND PROCESS FOR MANUFACTURE OF RELEASE LINERS MOMENTIVE PERFORMANCE MATERIALS INC. 2021-09-09 US disclosed
EP-1050538-B1 Irradiation-curable silicone compositions containing photo-active platinum (IV) compounds GEN ELECTRIC (US) 2004-08-04 EP disclosed
US-6150546-A AS HYDROSILYLATION CATALYST FOR EFFECTING THE CURE OF AN IRRADIATION-CURABLE SILICONE MIXTURE GENERAL ELECTRIC COMPANY (US) 2000-11-21 US disclosed
EP-1050538-A2 Irradiation-curable silicone compositions containing photo-active platinum (IV) compounds GENERAL ELECTRIC COMPANY (US) 2000-11-08 EP disclosed