SCHEMBL338936

SCHEMBL338936

O=C(O)c1c(O)c(-c2ccccc2)c2ccccc2c1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 4/20 0.49
LMNA P02545 3/20 0.49
PDE10A Q9Y233 2/20 0.49
KDM4E B2RXH2 6/20 0.43
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
HNF4A P41235 1/20 0.43
KMT2A Q03164 3/20 0.42
GLA P06280 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C19 P33261 1/20 0.42
MAPT P10636 2/20 0.42
TDP1 Q9NUW8 2/20 0.41
CYP3A4 P08684 1/20 0.40
CYP2C8 P10632 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL901570 0.89 DHODH (0.53) DHODHLMNAPDE10AKDM4EALDH1A1
SCHEMBL21879686 0.84 LMNA (0.51) DHODHLMNAPDE10AKDM4EALDH1A1
SCHEMBL29262209 0.84 LMNA (0.55) DHODHLMNAPDE10AKDM4EALDH1A1
SCHEMBL7537511 0.81 DHODH (0.52) DHODHPDE10AKDM4EALDH1A1HPGD
SCHEMBL901568 0.81 LMNA (0.53) DHODHLMNAPDE10AKDM4EALDH1A1
SCHEMBL27724475 0.80 LMNA (0.56) DHODHLMNAPDE10AKDM4EALDH1A1
SCHEMBL901598 0.79 HSD17B10 (0.48) DHODHPDE10AKDM4EALDH1A1HPGD
SCHEMBL27572021 0.79 HSD17B10 (0.48) DHODHPDE10AKDM4EALDH1A1HPGD
SCHEMBL2356921 0.78 DHODH (0.50) DHODHLMNAPDE10AKDM4EALDH1A1
SCHEMBL25177897 0.77 KDM4E (0.60) DHODHLMNAPDE10AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3719617-B1 MULTIFUNCTIONAL PEN MITSUBISHI PENCIL CO (JP) 2023-08-16 EP disclosed
US-11221686-B2 Multifunction pen MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2022-01-11 US disclosed
US-20200363881-A1 MULTIFUNCTION PEN MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2020-11-19 US disclosed
EP-3719617-A1 MULTIFUNCTIONAL PEN Mitsubishi Pencil Company, Limited (JP) 2020-10-07 EP disclosed
WO-2016198784-A1 THERMOCHROMIC MAKEUP OR TATTOOING MICROCAPSULES AND COMPOSITION INK AND OUT SAS (FR) 2016-12-15 WO disclosed
US-8616797-B2 Thermosensitive decolorable ink composition MITSUBISHI PENCIL COMPANY, LTD. (JP) 2013-12-31 US disclosed
EP-2412762-A1 THERMOSENSITIVE DECOLORABLE INK COMPOSITION Mitsubishi Pencil Company, Limited (JP) 2012-02-01 EP disclosed
US-20120014740-A1 THERMOSENSITIVE DECOLORABLE INK COMPOSITION MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2012-01-19 US disclosed