SCHEMBL7537511

SCHEMBL7537511

O=C(O)c1c(O)c(C(=O)O)c2ccccc2c1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 5/20 0.52
PDE10A Q9Y233 2/20 0.52
KDM4E B2RXH2 4/20 0.50
HPGD P15428 3/20 0.50
HSD17B10 Q99714 3/20 0.50
MEN1 O00255 2/20 0.50
ALDH1A1 P00352 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP1A2 P05177 1/20 0.50
GLA P06280 1/20 0.50
CYP2C19 P33261 1/20 0.50
TDP1 Q9NUW8 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
LDHA P00338 2/20 0.45
CYP2C9 P11712 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29260803 0.90 DHODH (0.55) DHODHPDE10AKDM4EHPGDHSD17B10
SCHEMBL901598 0.88 HSD17B10 (0.48) DHODHPDE10AKDM4EHPGDHSD17B10
SCHEMBL27572021 0.88 HSD17B10 (0.48) DHODHPDE10AKDM4EHPGDHSD17B10
SCHEMBL28261469 0.86 DHODH (0.52) DHODHPDE10AKDM4EHPGDHSD17B10
SCHEMBL31414101 0.85 HSD17B10 (0.54) DHODHPDE10AKDM4EHPGDHSD17B10
SCHEMBL4415520 0.85 HSD17B10 (0.54) DHODHPDE10AKDM4EHPGDHSD17B10
SCHEMBL54422 0.85 KDM4E (0.58) DHODHPDE10AKDM4EHPGDHSD17B10
SCHEMBL6450325 0.84 DHODH (0.50) DHODHPDE10AKDM4EHPGDHSD17B10
SCHEMBL31039922 0.84 DHODH (0.50) DHODHPDE10AKDM4EHPGDHSD17B10
SCHEMBL2477681 0.83 HSD17B10 (0.58) DHODHPDE10AKDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 DHODH 3329/4885PDE10A 1178/4885KDM4E 3406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.