Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A3 | O75751 | 2/20 | 1.00 |
| ▸ | SLC22A2 | O15244 | 1/20 | 1.00 |
| ▸ | SLC22A1 | O15245 | 1/20 | 1.00 |
| ▸ | NQO2 | P16083 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 14/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.98 |
| ▸ | HTT | P42858 | 11/20 | 0.98 |
| ▸ | POLB | P06746 | 11/20 | 0.98 |
| ▸ | MAPT | P10636 | 11/20 | 0.98 |
| ▸ | RAB9A | P51151 | 10/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.98 |
| ▸ | LMNA | P02545 | 9/20 | 0.98 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.98 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.98 |
| ▸ | PKM | P14618 | 6/20 | 0.98 |
| ▸ | RECQL | P46063 | 4/20 | 0.98 |
| ▸ | ALPG | P10696 | 3/20 | 0.98 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.98 |
| ▸ | BLM | P54132 | 4/20 | 0.76 |
| ▸ | THRB | P10828 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13619260 | 1.00 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| SCHEMBL29378931 | 1.00 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| SCHEMBL29832895 | 1.00 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| SCHEMBL3978997 | 1.00 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| Bromide SCHEMBL3389493 | 1.00 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| SCHEMBL737002 | 1.00 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| Iodide SCHEMBL8859608 | 0.99 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| Iodide SCHEMBL29462337 | 0.99 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| Hydrochloric Acid SCHEMBL4107666 | 0.99 | MEN1 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| Iodide SCHEMBL4779860 | 0.99 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100103355-A1 | COLOR CORRECTION FILTER, IMAGE DISPLAY, AND LIQUID CRYSTAL DISPLAY | NITTO DENKO CORPORATION (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20100039591-A1 | CROSSLINKED PRODUCT, COLOR CORRECTION FILTER, OPTICAL ELEMENT, IMAGE DISPLAY, AND LIQUID CRYSTAL DISPLAY | NITTO DENKO CORPORATION (JP) | 2010-02-18 | — | — | US | disclosed |