Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A3 | O75751 | 2/20 | 1.00 |
| ▸ | SLC22A2 | O15244 | 1/20 | 1.00 |
| ▸ | SLC22A1 | O15245 | 1/20 | 1.00 |
| ▸ | NQO2 | P16083 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 14/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.98 |
| ▸ | HTT | P42858 | 11/20 | 0.98 |
| ▸ | POLB | P06746 | 11/20 | 0.98 |
| ▸ | MAPT | P10636 | 11/20 | 0.98 |
| ▸ | RAB9A | P51151 | 10/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.98 |
| ▸ | LMNA | P02545 | 9/20 | 0.98 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.98 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.98 |
| ▸ | PKM | P14618 | 6/20 | 0.98 |
| ▸ | RECQL | P46063 | 4/20 | 0.98 |
| ▸ | ALPG | P10696 | 3/20 | 0.98 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.98 |
| ▸ | BLM | P54132 | 4/20 | 0.76 |
| ▸ | THRB | P10828 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3389494 | 1.00 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| SCHEMBL29378931 | 1.00 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| SCHEMBL29832895 | 1.00 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| SCHEMBL3978997 | 1.00 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| Bromide SCHEMBL3389493 | 1.00 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| SCHEMBL737002 | 1.00 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| Iodide SCHEMBL8859608 | 0.99 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| Iodide SCHEMBL29462337 | 0.99 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| Hydrochloric Acid SCHEMBL4107666 | 0.99 | MEN1 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 | |
| Iodide SCHEMBL4779860 | 0.99 | SLC22A3 (1.00) | SLC22A3SLC22A2SLC22A1NQO2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134877-A2 | THERAPEUTICS FOR TREATMENT RESISTANT MENTAL DISORDERS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-11-05 | — | — | WO | disclosed |
| US-20090221552-A1 | Methods for the Treatment of ADHD and Related Disorders | THE MCLEAN HOSPITAL CORPORATION (US) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221552-A1 | Methods for the Treatment of ADHD and Related Disorders | SLC6A3, SLC6A2, SLC6A4 | SLC22A3 105/4885SLC22A2 345/4885SLC22A1 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.