Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873372 | 0.88 | SLC18A3 (0.35) | SLC18A3SIGMAR1MEN1KMT2APRCP | |
| SCHEMBL3704857 | 0.80 | DDB1 (0.35) | MAPT | |
| SCHEMBL4703182 | 0.80 | CHRNB2 (0.56) | MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29882239 | 0.79 | DDB1 (0.34) | — | |
| SCHEMBL7068816 | 0.78 | MEN1 (0.39) | SLC18A3SIGMAR1MEN1KMT2APRCP | |
| SCHEMBL28159132 | 0.78 | SLC18A3 (0.40) | SLC18A3SIGMAR1MEN1KMT2APRCP | |
| SCHEMBL4165235 | 0.78 | SLC18A3 (0.40) | SLC18A3SIGMAR1MEN1KMT2APRCP | |
| Hydrochloric Acid SCHEMBL1566699 | 0.78 | CHRNB2 (0.54) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31544229 | 0.76 | HTR2C (0.46) | MEN1KMT2AGAAMAPT | |
| SCHEMBL7508696 | 0.75 | FAAH (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2166002-A1 | Chiral organic catalysts for the enantioselective reduction of n-alkyl and n-benzyl-substituted alicyclic and cyclic imines | UNIVERSITA'DEGLI STUDI DI MILANO (IT) | 2010-03-24 | — | — | EP | disclosed |