Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 17/20 | 0.65 |
| ▸ | CSGALNACT1 | Q8TDX6 | 2/20 | 0.65 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1762011 | 0.95 | DGAT1 (0.69) | DGAT1CSGALNACT1SCD | |
| Trifluoroacetic Acid SCHEMBL1761434 | 0.88 | DGAT1 (0.55) | DGAT1CSGALNACT1 | |
| SCHEMBL3389661 | 0.88 | DGAT1 (0.54) | DGAT1CSGALNACT1SCD | |
| SCHEMBL1762153 | 0.83 | DGAT1 (0.59) | DGAT1CSGALNACT1SCD | |
| Trifluoroacetic Acid SCHEMBL3387514 | 0.82 | DGAT1 (0.60) | DGAT1CSGALNACT1 | |
| Trifluoroacetic Acid SCHEMBL3391046 | 0.82 | DGAT1 (0.60) | DGAT1CSGALNACT1 | |
| SCHEMBL1761505 | 0.82 | DGAT1 (0.75) | DGAT1CSGALNACT1SCD | |
| SCHEMBL1761825 | 0.82 | DGAT1 (0.75) | DGAT1CSGALNACT1SCD | |
| SCHEMBL1761544 | 0.81 | DGAT1 (0.80) | DGAT1CSGALNACT1SCD | |
| SCHEMBL12648321 | 0.81 | DGAT1 (0.51) | DGAT1CSGALNACT1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805156-B1 | PREPARATION AND USE OF BIPHENYL-4-YL-CARBONYLAMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2010-12-22 | — | — | EP | disclosed |