Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 8/20 | 0.54 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.54 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 2/20 | 0.36 |
| ▸ | BRAF | P15056 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 2/20 | 0.35 |
| ▸ | NEK3 | P51956 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | NEK5 | Q6P3R8 | 1/20 | 0.34 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1761437 | 0.89 | DGAT1 (0.46) | DGAT1CSGALNACT1CYP2C9 | |
| Trifluoroacetic Acid SCHEMBL3389655 | 0.88 | DGAT1 (0.65) | DGAT1CSGALNACT1SCD | |
| SCHEMBL1762011 | 0.86 | DGAT1 (0.69) | DGAT1CSGALNACT1SCDNPC1RAB9A | |
| SCHEMBL3387517 | 0.83 | DGAT1 (0.50) | DGAT1CSGALNACT1PDE10ACYP2C9NPC1 | |
| SCHEMBL3391052 | 0.83 | DGAT1 (0.50) | DGAT1CSGALNACT1PDE10ACYP2C9NPC1 | |
| SCHEMBL12648321 | 0.79 | DGAT1 (0.51) | DGAT1CSGALNACT1RAF1BRAFPDE10A | |
| Trifluoroacetic Acid SCHEMBL1761434 | 0.77 | DGAT1 (0.55) | DGAT1CSGALNACT1 | |
| SCHEMBL1762153 | 0.75 | DGAT1 (0.59) | DGAT1CSGALNACT1SCD | |
| SCHEMBL1761354 | 0.74 | DGAT1 (0.44) | DGAT1CSGALNACT1MPL | |
| SCHEMBL1761469 | 0.74 | DGAT1 (0.42) | DGAT1CSGALNACT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805156-B1 | PREPARATION AND USE OF BIPHENYL-4-YL-CARBONYLAMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2010-12-22 | — | — | EP | disclosed |