Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.56 |
| ▸ | BCL2 | P10415 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | RPA1 | P27694 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 3/20 | 0.44 |
| ▸ | FABP3 | P05413 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389952 | 0.90 | MALT1 (0.52) | NPC1RAB9AMDM2MCL1BCL2 | |
| SCHEMBL6344046 | 0.85 | PTGS2 (0.66) | PTGS1PTGS2CA9CYP2C9 | |
| SCHEMBL29074654 | 0.83 | MDM2 (0.53) | NPC1RAB9AMDM2MCL1BCL2 | |
| SCHEMBL10504777 | 0.82 | NPC1 (0.54) | NPC1RAB9AMDM2MCL1BCL2 | |
| SCHEMBL11431929 | 0.82 | HTT (0.61) | NPC1RAB9AMDM2MCL1BCL2 | |
| SCHEMBL17290871 | 0.81 | BCL2 (0.46) | MDM2MCL1BCL2ALDH1A1HPGD | |
| SCHEMBL11444157 | 0.81 | NPC1 (0.49) | NPC1RAB9AMDM2MCL1BCL2 | |
| SCHEMBL29074642 | 0.81 | HTT (0.59) | NPC1RAB9AMDM2MCL1BCL2 | |
| SCHEMBL11497254 | 0.80 | MDM2 (0.50) | NPC1RAB9AMDM2MCL1BCL2 | |
| SCHEMBL11650362 | 0.79 | MAPK1 (0.56) | NPC1RAB9AMDM2MCL1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858675-B2 | Composition with polymer and an oxidation-catalyst | DSM IP ASSETS B.V. (NL) | 2010-12-28 | — | — | US | disclosed |
| EP-2038340-B1 | PROCESS FOR IMPROVING THE BIODEGRADABILITY OF A POLYMER | DSM IP ASSETS BV (NL) | 2010-12-22 | — | — | EP | disclosed |
| US-20100048764-A1 | adding 1,2-oxo-hydroxy compound for catalyzing and increasing the rate of biodegradation of a polymer to carbon dioxide and water; low density polymer, linear low density polymer, or high density of polyethylene, or polypropylene and their copolymers; environmentally friendly; free of transition metals | DSM IP ASSETS B.V. (NL) | 2010-02-25 | — | — | US | disclosed |
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2038340-A1 | PROCESS FOR IMPROVING THE BIODEGRADABILITY OF A POLYMER | DSMIP Assets B.V. (NL) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008006492-A1 | PROCESS FOR IMPROVING THE BIODEGRADABILITY OF A POLYMER | DSM IP ASSETS B.V. (NL) | 2008-01-17 | — | — | WO | disclosed |