Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.52 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.52 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | FABP3 | P05413 | 2/20 | 0.49 |
| ▸ | FABP4 | P15090 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 2/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RPA1 | P27694 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389753 | 0.90 | NPC1 (0.57) | PTGS2FABP3FABP4SIGMAR1BCL2 | |
| SCHEMBL6344046 | 0.81 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL17156386 | 0.81 | CACNA1B (0.53) | MALT1SLC16A3PTGS2 | |
| SCHEMBL29074646 | 0.80 | L3MBTL1 (0.54) | MALT1SLC16A3SLC16A1PTGS2FABP3 | |
| SCHEMBL25397697 | 0.79 | L3MBTL1 (0.62) | MALT1SLC16A3SLC16A1FABP3FABP4 | |
| SCHEMBL7156590 | 0.78 | MALT1 (0.58) | MALT1SLC16A3SLC16A1FABP3FABP4 | |
| SCHEMBL5698704 | 0.77 | NPC1 (0.78) | MALT1SLC16A3SLC16A1PTGS2L3MBTL1 | |
| SCHEMBL10504777 | 0.76 | NPC1 (0.54) | FABP3FABP4SIGMAR1BCL2MDM2 | |
| SCHEMBL11437628 | 0.76 | L3MBTL1 (0.55) | MALT1SLC16A3SLC16A1FABP3FABP4 | |
| SCHEMBL5150511 | 0.76 | MDM2 (0.56) | PTGS2FABP3FABP4BCL2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |