SCHEMBL3389813

SCHEMBL3389813

O=C(O)C1CC2CCCCC2C(C(=O)O)C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 1/20 0.38
HSD11B1 P28845 1/20 0.34
ACE P12821 1/20 0.32
SLC1A2 P43004 2/20 0.32
SLC1A1 P43005 2/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C1 Q04828 1/20 0.32
SLC6A1 P30531 2/20 0.31
TSHR P16473 2/20 0.31
SLC6A11 P48066 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SLC6A13 Q9NSD5 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1079326 0.87 GABRR1 (0.39) GABRR1HSD11B1SLC1A2SLC1A1
SCHEMBL10709007 0.83 GABRR1 (0.41) GABRR1ACESLC1A2SLC1A1AKR1C3
SCHEMBL29755676 0.83 HSD11B1 (0.36) GABRR1HSD11B1SLC6A1TSHRSLC6A11
SCHEMBL30489364 0.83 GABRR1 (0.39) GABRR1SLC1A2SLC1A1
SCHEMBL1073547 0.80 TSHR (0.40) GABRR1HSD11B1ACESLC1A2SLC1A1
SCHEMBL23702736 0.80 HSD11B1 (0.38) GABRR1HSD11B1ACESLC1A2SLC1A1
SCHEMBL3391540 0.80 GABRR1 (0.38) GABRR1ACEAKR1C3AKR1C1LMNA
SCHEMBL6057596 0.80 GABRR1 (0.33) GABRR1HSD11B1SLC1A2SLC1A1
SCHEMBL9019456 0.79 SLC1A2 (0.39) GABRR1HSD11B1SLC1A2SLC1A1
SCHEMBL12463875 0.78 GABRR1 (0.41) GABRR1SLC1A2SLC1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12534568-B2 Polyester carbonates consisting of different diols in a defined ratio COVESTRO DEUTSCHLAND AG (DE) 2026-01-27 US claimed
EP-4168468-B1 POLYESTER CARBONATES MADE FROM CYCLOALIPHATIC DIACIDS, 1,4 : 3,6-DIANHYDRO-HEXITOLE AND A FURTHER ALIPHATIC DIHYDROXY COMPOUND COVESTRO DEUTSCHLAND AG (DE) 2025-04-02 EP claimed
CN-114599706-B Process for preparing polyester carbonates 科思创德国股份有限公司 2025-02-18 CN claimed
US-20230340190-A1 Polyester Carbonates From Cycloaliphatic Diacids, 1,4:3,6-Dianhydrohexitol and a Further Aliphatic Dihydroxy Compound COVESTRO DEUTSCHLAND AG (DE) 2023-10-26 US claimed
US-11732089-B2 Highly heat-resistant and highly transparent polycarbonate ester, and preparation method therefor SK CHEMICALS CO., LTD. (KR) 2023-08-22 US claimed
US-20230145772-A1 Polyester Carbonates Consisting of Different Diols in a Defined Ratio COVESTRO DEUTSCHLAND AG (DE) 2023-05-11 US claimed
EP-4168467-A1 POLYESTER CARBONATES ON THE BASIS OF CYCLOALIPHATIC DIACIDS, 1,4:3,6-DIANHYDROHEXITOL AND SPECIFIC AMOUNTS OF AN ADDITIONAL ALIPHATIC DIHYDROXY COMPOUND Covestro Deutschland AG (DE) 2023-04-26 EP claimed
EP-4168468-A1 POLYESTER CARBONATES CONSISTING OF DIFFERENT DIOLS IN A DEFINED RATIO Covestro Deutschland AG (DE) 2023-04-26 EP claimed
EP-4168469-A1 POLYESTER CARBONATES FROM CYCLOALIPHATIC DIACIDS, 1,4:3,6-DIANHYDROHEXITOL AND A FURTHER ALIPHATIC DIHYDROXY COMPOUND Covestro Deutschland AG (DE) 2023-04-26 EP claimed
CN-113166384-B Polyester carbonates made from cycloaliphatic diacids and aliphatic diols and methods for making the same 科思创知识产权两合公司 2023-02-17 CN claimed
US-20180223041-A1 Highly Heat-Resistant And Highly Transparent Polycarbonate Ester, And Preparation Method Therefor SK CHEMICALS CO., LTD. 2018-08-09 US claimed
EP-3026074-B1 HIGHLY HEAT-RESISTANT AND HIGHLY TRANSPARENT POLYCARBONATE ESTER, AND PREPARATION METHOD THEREFOR SK CHEMICALS CO LTD (KR) 2018-05-30 EP claimed
US-20170369641-A1 NOVEL METHOD FOR PREPARING HIGHLY TRANSPARENT AND HIGHLY HEAT-RESISTANT POLYCARBONATE ESTER SK CHEMICALS CO., LTD. (KR) 2017-12-28 US claimed
EP-3248999-A1 NOVEL METHOD FOR PREPARING HIGHLY TRANSPARENT AND HIGHLY HEAT-RESISTANT POLYCARBONATE ESTER SK Chemicals Co., Ltd. (KR) 2017-11-29 EP claimed
CN-105392818-B High-fire resistance high grade of transparency makrolon and preparation method thereof SK化学公司 2017-11-28 CN claimed
CN-107108870-A Prepare the new method of the makrolon with the high grade of transparency and high-fire resistance SK化学公司 2017-08-29 CN claimed
US-20170166693-A1 HIGHLY HEAT-RESISTANT AND HIGHLY TRANSPARENT POLYCARBONATE ESTER, AND PREPARATION METHOD THEREFOR SK CHEMICALS CO., LTD. 2017-06-15 US claimed
US-20160152767-A1 HIGHLY HEAT-RESISTANT AND HIGHLY TRANSPARENT POLYCARBONATE ESTER, AND PREPARATION METHOD THEREFOR SK CHEMICALS CO., LTD. (KR) 2016-06-02 US claimed
EP-3026074-A1 HIGHLY HEAT-RESISTANT AND HIGHLY TRANSPARENT POLYCARBONATE ESTER, AND PREPARATION METHOD THEREFOR SK Chemicals Co., Ltd. (KR) 2016-06-01 EP claimed
WO-1999061506-A1 THERMOSETTING COATING COMPOSITIONS BASED ON POLYESTERS EASTMAN CHEMICAL COMPANY (US) 1999-12-02 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534568-B2 Polyester carbonates consisting of different diols in a defined ratio HSD11B2, HSD11B1, HSD3B1 GABRR1 1461/4885HSD11B1 2/4885ACE 1919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.