Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4144107 | 0.77 | CYP3A4 (0.47) | CYP3A4LMNAKDM4EMAPTRAB9A | |
| SCHEMBL31531653 | 0.77 | CYP3A4 (0.47) | CYP3A4LMNAKDM4EMAPTRAB9A | |
| SCHEMBL1147248 | 0.76 | KDM4E (0.39) | ADRA2AADRA2CKDM4EMAPTRAB9A | |
| SCHEMBL30049919 | 0.75 | CYP19A1 (0.38) | ADRA2AADRA2CKDM4EMAPTRAB9A | |
| SCHEMBL4486896 | 0.74 | RAD52 (0.39) | CYP3A4ADRA2AADRA2CADRA2BLMNA | |
| SCHEMBL4503223 | 0.73 | MAPK10 (0.50) | CYP3A4ADRA2AADRA2CADRA2BLMNA | |
| SCHEMBL29666517 | 0.72 | KDM4E (0.53) | LMNAKDM4EMAPTRAB9ANPC1 | |
| SCHEMBL3190092 | 0.71 | AHR (0.45) | CYP3A4KDM4ERAB9ASIRT2SIRT1 | |
| SCHEMBL1395066 | 0.70 | TGFBR1 (0.36) | ADRA2AADRA2CKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL29852620 | 0.70 | MAPT (0.54) | CYP3A4LMNAKDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292269-B1 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | HENKEL KGAA (DE) | 2005-02-09 | — | — | EP | claimed |
| US-20230158156-A1 | BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF | FLAGSHIP PIONEERING, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| EP-1432390-B2 | DYEING COMPOSITION WITH A BRIGHTENING EFFECT FOR HAIR | ORÉAL L (FR) | 2015-04-15 | — | — | EP | disclosed |
| EP-1432390-B1 | DYEING COMPOSITION WITH A BRIGHTENING EFFECT FOR HAIR | OREAL (FR) | 2010-12-15 | — | — | EP | disclosed |
| US-7217296-B2 | Dyeing composition with a lightening effect for human keratin materials comprising at least one fluorescent dye | L'OREAL S.A. (FR) | 2007-05-15 | — | — | US | disclosed |
| EP-1292268-B1 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | HENKEL KGAA (DE) | 2005-02-23 | — | — | EP | disclosed |
| US-20050028301-A1 | Dyeing composition with a brightening effect for human kerationous fibres | L'OREAL S.A. (FR) | 2005-02-10 | — | — | US | disclosed |
| EP-1292269-B1 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | HENKEL KGAA (DE) | 2005-02-09 | — | — | EP | disclosed |
| EP-1432390-A1 | DYEING COMPOSITION WITH A BRIGHTENING EFFECT FOR HUMAN KERATINOUS FIBRES | L'OREAL (FR) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028685-A1 | DYEING COMPOSITION WITH A BRIGHTENING EFFECT FOR HUMAN KERATINOUS FIBRES | L'OREAL (FR) | 2003-04-10 | — | — | WO | disclosed |
| EP-1292268-A2 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-03-19 | — | — | EP | disclosed |
| EP-1292269-A1 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001097764-A3 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | HENKEL KGAA (DE) | 2002-05-23 | — | — | WO | disclosed |
| WO-2001097764-A2 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-27 | — | — | WO | disclosed |
| WO-2001097765-A1 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050028301-A1 | Dyeing composition with a brightening effect for human kerationous fibres | KRT18, IK, KIF5B | CYP3A4 2144/4885ADRA2A 4176/4885ADRA2C 3849/4885 |
| US-20230158156-A1 | BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF | EFTUD2, SNRPE, DDX21 | CYP3A4 4823/4885ADRA2A 4683/4885ADRA2C 4647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.