Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657184 | 0.88 | KDM4E (0.51) | KDM4EHTTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL20476391 | 0.81 | KMT2A (0.42) | KDM4EMAPK1ALDH1A1GAAMEN1 | |
| SCHEMBL13173077 | 0.78 | KDM4E (0.50) | KDM4EHTTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL31723844 | 0.78 | L3MBTL1 (0.47) | KDM4EHTTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL22251040 | 0.77 | KDM4E (0.54) | KDM4EHTTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL17424052 | 0.76 | KDM4E (0.72) | KDM4EHTTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL9090652 | 0.76 | KDM4E (0.68) | KDM4EHTTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL12885411 | 0.76 | KDM4E (0.43) | KDM4EHTTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL20476323 | 0.76 | MAPT (0.50) | HTTMAPK1ALDH1A1TSHRPOLB | |
| SCHEMBL11864751 | 0.74 | KDM4E (0.58) | KDM4EHTTMAPK1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078165-B2 | Compounds for treating tuberculosis | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2021-08-03 | — | — | US | disclosed |
| US-20200231550-A1 | COMPOUNDS FOR TREATING TUBERCULOSIS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2020-07-23 | — | — | US | disclosed |
| EP-2241555-A1 | New RAC1 inhibitors as potential pharmacological agents for heart failure treatment | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2010-10-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078165-B2 | Compounds for treating tuberculosis | ATP5ME, ATP5MG, ATP5F1D | KDM4E 2150/4885HTT 4338/4885MAPK1 3391/4885 |
| US-20200231550-A1 | COMPOUNDS FOR TREATING TUBERCULOSIS | ATP5ME, ATP5MG, ATP5F1D | KDM4E 2150/4885HTT 4338/4885MAPK1 3391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.