Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25003463 | 0.88 | FFAR1 (0.34) | FFAR1GPR84 | |
| SCHEMBL10633576 | 0.81 | GAA (0.32) | FFAR1GPR84 | |
| SCHEMBL9228623 | 0.80 | NR1I2 (0.36) | GPR84 | |
| SCHEMBL5851068 | 0.76 | FFAR1 (0.42) | FFAR1GPR84 | |
| SCHEMBL13848526 | 0.76 | ADRA2A (0.31) | GPR84 | |
| SCHEMBL22819103 | 0.76 | NR1I2 (0.38) | GPR84 | |
| SCHEMBL21101056 | 0.76 | NR1I2 (0.38) | GPR84 | |
| SCHEMBL25866564 | 0.76 | NR1I2 (0.38) | GPR84 | |
| SCHEMBL27846459 | 0.75 | SMN1; SMN2 (0.33) | FFAR1GPR84 | |
| SCHEMBL20372779 | 0.74 | NR1I2 (0.37) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094721-A1 | PIPERIDIN-PYRIMIDINE DERIVATIVES AS ANTAGONISTS OF HISTAMINE H4 RECEPTOR | PALAU PHARMA, S. A. (ES) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010043633-A1 | 2H-PYRAZOLO [4,3-D]PYRIMIDIN-5-AMINE DERIVATIVES AS H4 HISTAMINE RECEPTOR ANTAGONISTS FOR THE TREATMENT OF ALLERGIC, IMMUNOLOGICAL AND INFLAMMATORY DISEASES | PALAU PHARMA, S. A. (ES) | 2010-04-22 | — | — | WO | disclosed |