SCHEMBL25003463

SCHEMBL25003463

CCCC(CCC)c1ccc[nH]1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.34
GPR84 Q9NQS5 1/20 0.34
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
NQO1 P15559 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10633576 0.92 GAA (0.32) FFAR1GPR84
SCHEMBL9228623 0.91 NR1I2 (0.36) GPR84
SCHEMBL3390190 0.88 FFAR1 (0.31) FFAR1GPR84
SCHEMBL22819103 0.86 NR1I2 (0.38) GPR84
SCHEMBL25866564 0.86 NR1I2 (0.38) GPR84
SCHEMBL21101056 0.86 NR1I2 (0.38) GPR84
SCHEMBL20098207 0.84 NR1I2 (0.37) GPR84
SCHEMBL19198110 0.84 NR1I2 (0.37) GPR84
SCHEMBL20372779 0.84 NR1I2 (0.37) GPR84
SCHEMBL5851068 0.83 FFAR1 (0.42) FFAR1GPR84NQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230279052-A1 PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-09-07 US disclosed
US-20230045142-A1 SMALL MOLECULE RPN13 INHIBITORS WITH ANTITUMOR PROPERTIES THE JOHNS HOPKINS UNIVERSITY (US) 2023-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230279052-A1 PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES ARG2, NLN, OAT FFAR1 2840/4885GPR84 1120/4885ESR1 3638/4885
US-20230045142-A1 SMALL MOLECULE RPN13 INHIBITORS WITH ANTITUMOR PROPERTIES MRPS23, RPP30, RPS19 FFAR1 4101/4885GPR84 3786/4885ESR1 2627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.