SCHEMBL3390193

SCHEMBL3390193

O=C(O)N1CCC[C@H]1c1ncc(-c2cnc(-c3ccc(-c4cnc([C@@H]5CCCN5C(=O)OCc5ccccc5)[nH]4)cc3)nc2)[nH]1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRCP P42785 11/20 0.52
HPGDS O60760 5/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3390204 1.00 PRCP (0.52) PRCPHPGDS
SCHEMBL691476 0.92 HPGDS (0.61) PRCPHPGDS
SCHEMBL691477 0.92 HPGDS (0.61) PRCPHPGDS
SCHEMBL13501764 0.92 HPGDS (0.61) PRCPHPGDS
SCHEMBL16511508 0.91 PRCP (0.52) PRCPHPGDS
SCHEMBL12174996 0.91 PRCP (0.61) PRCP
SCHEMBL12160098 0.91 PRCP (0.61) PRCP
SCHEMBL12160053 0.91 PRCP (0.61) PRCP
SCHEMBL14302085 0.90 PRCP (0.50) PRCPHPGDS
SCHEMBL4524622 0.90 PRCP (0.59) PRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2242752-A1 IMIDAZOLYL BIPHENYL IMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS Bristol-Myers Squibb Company (US) 2010-10-27 EP disclosed
WO-2009102325-A1 IMIDAZOLYL BIPHENYL IMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2009-08-20 WO disclosed
EP-2049522-A2 HEPATITIS C VIRUS INHIBITORS Brystol-Myers Squibb Company (US) 2009-04-22 EP disclosed
WO-2008021927-A2 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2008-02-21 WO disclosed