Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 11/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12174996 | 0.97 | PRCP (0.61) | PRCPOPRM1OPRD1 | |
| SCHEMBL12160053 | 0.97 | PRCP (0.61) | PRCPOPRM1OPRD1 | |
| SCHEMBL12160098 | 0.97 | PRCP (0.61) | PRCPOPRM1OPRD1 | |
| SCHEMBL2708434 | 0.93 | PRCP (0.55) | PRCPOPRM1OPRD1 | |
| SCHEMBL12175006 | 0.93 | PRCP (0.55) | PRCPOPRM1OPRD1 | |
| SCHEMBL205415 | 0.93 | PRCP (0.55) | PRCPOPRM1OPRD1 | |
| SCHEMBL8749176 | 0.92 | PRCP (0.69) | PRCP | |
| SCHEMBL19578040 | 0.92 | PRCP (0.58) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL10076571 | 0.91 | PRCP (0.59) | PRCPOPRM1OPRD1 | |
| SCHEMBL3390193 | 0.90 | PRCP (0.52) | PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318445-A1 | PDF INHIBITORS | NORVARTIS AG (CH) | 2009-12-24 | — | — | US | disclosed |
| EP-1973898-A1 | PDF INHIBITORS | Novartis AG (CH) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007077186-A1 | PDF INHIBITORS | NOVARTIS AG (CH) | 2007-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318445-A1 | PDF INHIBITORS | PDF, TIMP3, MMP2 | PRCP 161/4885OPRM1 4282/4885OPRD1 4141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.