SCHEMBL3390294

SCHEMBL3390294

C=CN1C(=O)NC(C)(CC)C1=O

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
FPR2 P25090 3/20 0.37
ALDH1A1 P00352 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.33
POLB P06746 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2030442 0.74 POLB (0.46) ALDH1A1POLBGAA
SCHEMBL11387071 0.73 FPR2 (0.38) NPC1RAB9AFPR2ALDH1A1POLB
SCHEMBL15026088 0.72 CYP2C19 (0.46) NPC1RAB9AFPR2ALDH1A1L3MBTL1
SCHEMBL19853470 0.71 FPR2 (0.47) NPC1RAB9AFPR2ALDH1A1L3MBTL1
SCHEMBL20614629 0.71 FPR2 (0.47) NPC1RAB9AFPR2ALDH1A1L3MBTL1
SCHEMBL22919778 0.71 FPR2 (0.39) NPC1RAB9AFPR2ALDH1A1L3MBTL1
SCHEMBL28875591 0.71 FPR2 (0.41) NPC1RAB9AFPR2ALDH1A1L3MBTL1
SCHEMBL11061919 0.71 FPR2 (0.42) NPC1RAB9AFPR2ALDH1A1L3MBTL1
SCHEMBL2556377 0.71 FPR2 (0.41) NPC1RAB9AFPR2ALDH1A1L3MBTL1
SCHEMBL23130049 0.69 FPR2 (0.43) NPC1RAB9AFPR2ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1964863-B1 Substantially linear polymers and methods of making the same ROHM & HAAS (US) 2009-09-02 EP claimed
US-7524905-B2 Substantially linear copolymers and methods of making the same ROHM AND HAAS COMPANY (US) 2009-04-28 US claimed
EP-1964863-A1 Substantially linear polymers and methods of making the same Rohm and Haas Company (US) 2008-09-03 EP claimed
US-20080207854-A1 Substantially linear copolymers and methods of making the same ROHM AND HAAS COMPANY 2008-08-28 US claimed
EP-3190120-B1 CATALYST FOR SYNTHESIZING POLYOLEFINS UNIV TOKYO (JP) 2021-11-17 EP disclosed
EP-2848623-B1 CATALYST FOR SYNTHESIZING POLYOLEFINS UNIV TOKYO (JP) 2017-09-27 EP disclosed
EP-3190120-A1 CATALYST FOR SYNTHESIZING POLYOLEFINS The University Of Tokyo (JP) 2017-07-12 EP disclosed
US-9303101-B2 Catalyst for synthesizing polyolefins THE UNIVERSITY OF TOKYO (JP) 2016-04-05 US disclosed
US-20150099857-A1 CATALYST FOR SYNTHESIZING POLYOLEFINS SHOWA DENKO K.K. (JP) 2015-04-09 US disclosed
EP-2848623-A1 CATALYST FOR SYNTHESIZING POLYOLEFINS The University of Tokyo (JP) 2015-03-18 EP disclosed
EP-1964862-B1 Composition and method for preparing linear copolymers of polar and non-polar olefins free of free radical initiated polymer ROHM & HAAS (US) 2010-12-22 EP disclosed
EP-1964863-B1 Substantially linear polymers and methods of making the same ROHM & HAAS (US) 2009-09-02 EP disclosed
US-7524912-B2 Preparation of linear ethylene-acrylate copolymers with palladium catalysts and free radical scavengers ROHM AND HAAS COMPANY (US) 2009-04-28 US disclosed
US-7524905-B2 Substantially linear copolymers and methods of making the same ROHM AND HAAS COMPANY (US) 2009-04-28 US disclosed
EP-1964862-A1 Composition and method for preparing linear copolymers of polar and non-polar olefins absent free radical addition polymer Rohm and Haas Company (US) 2008-09-03 EP disclosed
EP-1964863-A1 Substantially linear polymers and methods of making the same Rohm and Haas Company (US) 2008-09-03 EP disclosed
EP-1964859-A1 A porous linear polymer composition Rohm and Haas Company (US) 2008-09-03 EP disclosed
US-20080207789-A1 Porous linear polymer composition ACHOLLA FRANCIS V 2008-08-28 US disclosed
US-20080207854-A1 Substantially linear copolymers and methods of making the same ROHM AND HAAS COMPANY 2008-08-28 US disclosed
US-20080207856-A1 Composition and method for preparing copolymers of polar and non-polar olefins substantially free of free radical initiated polymer ROHM AND HAAS COMPANY 2008-08-28 US disclosed