Okadaic Acid

SCHEMBL3390447

C=C1[C@@H](O)[C@@H]2O[C@]3(CC[C@H](/C=C/[C@@H](C)[C@@H]4CC(C)=C[C@@]5(O[C@H](C[C@@](C)(O)C(=O)O)CC[C@H]5O)O4)O3)CC[C@H]2O[C@@H]1[C@@H](O)C[C@H](C)[C@H]1O[C@@]2(CCCCO2)CC[C@H]1C.OCCO

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	PPM1B	O75688	2/20	0.97

▸	PPP2CA	P67775	2/20	0.97

▸	PTPN1	P18031	1/20	0.97

▸	PPP1CC	P36873	1/20	0.97

▸	TFPI2	P48307	1/20	0.97

▸	NPY4R	P50391	1/20	0.97

▸	PPP2R5A	Q15172	1/20	0.97

▸	MAPT	P10636	1/20	0.97

▸	PPP6C	O00743	1/20	0.97

▸	PPP5C	P53041	1/20	0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Okadaic Acid SCHEMBL22024950	0.98	PPM1B (1.00)	PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL21408784	0.98	PPM1B (1.00)	PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL17899362	0.98	PPM1B (1.00)	PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL23350437	0.98	PPM1B (1.00)	PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL2386832	0.98	PPM1B (1.00)	PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL24418495	0.98	PPM1B (1.00)	PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL131485	0.98	PPM1B (1.00)	PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL545397	0.98	PPM1B (0.99)	PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL4446706	0.98	PPM1B (0.99)	PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL545387	0.98	PPM1B (0.99)	PPM1BPPP2CAPTPN1PPP1CCTFPI2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010051532-A1	COMPOSITIONS AND METHODS RELATED TO OBSTRUCTIVE SLEEP APNEA	UNIVERSITY OF CHICAGO (US)	2010-05-06	—	—	WO	disclosed
EP-0551200-A1	Protein phosphatase inhibitors for use in therapy	NATIONAL UNIVERSITY OF SINGAPORE (SG)	1993-07-14	—	—	EP	disclosed