Okadaic Acid

Okadaic Acid

SCHEMBL29369982

C=C1[C@@H](O)[C@@H]2O[C@@]3(CCC2O[C@@H]1[C@@H](O)C[C@H](C)C1O[C@@]2(CCCCO2)CC[C@H]1C)CC[C@H](/C=C/[C@@H](C)[C@@H]1CC(C)=C[C@@]2(O[C@H](C[C@@](C)(O)C(=O)O)CC[C@H]2O)O1)O3.N

nearest known ligand 0.99

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 2/20 0.99
PPP2CA P67775 2/20 0.99
PTPN1 P18031 1/20 0.99
PPP1CC P36873 1/20 0.99
TFPI2 P48307 1/20 0.99
NPY4R P50391 1/20 0.99
PPP2R5A Q15172 1/20 0.99
MAPT P10636 1/20 0.99
PPP6C O00743 1/20 0.99
PPP5C P53041 1/20 0.99

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Okadaic Acid SCHEMBL544727 1.00 PPM1B (0.99) PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL131485 0.99 PPM1B (1.00) PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL22024950 0.99 PPM1B (1.00) PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL21408784 0.99 PPM1B (1.00) PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL24418495 0.99 PPM1B (1.00) PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL23350437 0.99 PPM1B (1.00) PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL2386832 0.99 PPM1B (1.00) PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL17899362 0.99 PPM1B (1.00) PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL545397 0.99 PPM1B (0.99) PPM1BPPP2CAPTPN1PPP1CCTFPI2
Okadaic Acid SCHEMBL4446706 0.99 PPM1B (0.99) PPM1BPPP2CAPTPN1PPP1CCTFPI2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12508249-B2 Methods related to administering immunosuppressants and non-allergenic antigens to reduce or prevent anaphylaxis Cartesian Therapeutics Inc. (US) 2025-12-30 US disclosed
US-12472167-B2 Methods providing a therapeutic macromolecule and synthetic nanocarriers comprising immunosuppressant locally and concomitantly to reduce both Type 1 and Type IV hypersensitivity CARTESIAN THERAPEUTICS, INC. (US) 2025-11-18 US disclosed
EP-4568750-A1 COMPOSITIONS AND METHODS RELATED TO IMMUNOGLOBULIN PROTEASES AND FUSIONS THEREOF Cartesian Therapeutics, Inc. (US) 2025-06-18 EP disclosed
US-12324826-B2 Compositions and methods to mitigate or prevent an immune response to an immunogenic therapeutic molecule in non-human primates JOMOCO, CORP. (US) 2025-06-10 US disclosed
US-20250177360-A1 METHODS RELATED TO ADMINISTERING IMMUNOSUPPRESSANTS AND THERAPEUTIC MACROMOLECULES AT A REDUCED PHARMACODYNAMICALLY EFFECTIVE DOSE CARTESIAN THERAPEUTICS, INC. (US) 2025-06-05 US disclosed
EP-3858348-B1 REPEATED ADMINISTRATION OF NON-IMMUNOSUPRESSIVE ANTIGEN SPECIFIC IMMUNOTHERAPEUTICS CARTESIAN THERAPEUTICS INC (US) 2025-02-12 EP disclosed
CN-118987263-A Methods and compositions for enhancing CD4+ regulatory T cells 西莱克塔生物科技公司 2024-11-22 CN disclosed
WO-2024229350-A1 IMMUNOSUPPRESSANT IN COMBINATION WITH HIGH AFFINITY IL-2 RECEPTOR AGONISTS FOR DIABETES CARTESIAN THERAPEUTICS, INC. (US) 2024-11-07 WO disclosed
WO-2024229380-A1 IMMUNOSUPPRESSANT IN COMBINATION WITH HIGH AFFINITY IL-2 RECEPTOR AGONISTS IN AUTOIMMUNE LIVER DISEASES CARTESIAN THERAPEUTICS, INC. (US) 2024-11-07 WO disclosed
WO-2024229370-A1 COMPOSITIONS AND METHODS FOR TREATING GVHD CARTESIAN THERAPEUTICS, INC. (US) 2024-11-07 WO disclosed
US-20220354947-A1 METHODS FOR PROVIDING POLYMERIC SYNTHETIC NANOCARRIERS FOR GENERATING ANTIGEN-SPECIFIC TOLERANCE IMMUNE RESPONSES SELECTA BIOSCIENCES, INC. (US) 2022-11-10 US disclosed
US-20220323607-A1 SYNTHETIC NANOCARRIERS COMPRISING AN IMMUNOSUPPRESSANT IN COMBINATION WITH HIGH AFFINITY IL-2 RECEPTOR AGONISTS TO ENHANCE IMMUNE TOLERANCE SELECTA BIOSCIENCES, INC. (US) 2022-10-13 US disclosed
WO-2022217095-A1 SYNTHETIC NANOCARRIERS COMPRISING AN IMMUNOSUPPRESSANT IN COMBINATION WITH HIGH AFFINITY IL-2 RECEPTOR AGONISTS TO ENHANCE IMMUNE TOLERANCE SELECTA BIOSCIENCES, INC. (US) 2022-10-13 WO disclosed
WO-2022150335-A1 VIRAL VECTOR DOSING PROTOCOLS SELECTA BIOSCIENCES, INC. (US) 2022-07-14 WO disclosed
WO-2022098901-A1 COMPOSITIONS FOR REDUCING IMMUNE RESPONSES AGAINST IMMUNOGLOBULIN PROTEASES SELECTA BIOSCIENCES, INC. (US) 2022-05-12 WO disclosed
US-20220133864-A1 METHODS AND COMPOSITIONS FOR REDUCING IMMUNE RESPONSES AGAINST IMMUNOGLOBULIN PROTEASES SELECTA BIOSCIENCES INC (US) 2022-05-05 US disclosed
US-11298342-B2 Methods providing a therapeutic macromolecule and synthetic nanocarriers comprising immunosuppressant locally and concomitantly to reduce both type I and type IV hypersensitivity SELECTA BIOSCIENCES, INC. (US) 2022-04-12 US disclosed
US-20220071968-A1 METHODS OF ADMINISTERING IMMUNOSUPPRESSANTS HAVING A SPECIFIED PHARMACODYNAMIC EFFECTIVE LIFE AND THERAPEUTIC MACROMOLECULES FOR THE INDUCTION OF IMMUNE TOLERANCE SELECTA BIOSCIENCES, INC. (US) 2022-03-10 US disclosed
EP-3962537-A1 METHODS FOR TREATMENT OF SUBJECTS WITH PREEXISTING IMMUNITY TO VIRAL TRANSFER VECTORS Selecta Biosciences, Inc. (US) 2022-03-09 EP disclosed
US-11235057-B2 Methods for providing polymeric synthetic nanocarriers for generating antigen-specific tolerance immune responses SELECTA BIOSCIENCES, INC. (US) 2022-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220133864-A1 METHODS AND COMPOSITIONS FOR REDUCING IMMUNE RESPONSES AGAINST IMMUNOGLOBULIN PROTEASES FCGR3B, SERPINB1, SERPINA6 PPM1B 1444/4885PPP2CA 610/4885PTPN1 556/4885
US-20250177360-A1 METHODS RELATED TO ADMINISTERING IMMUNOSUPPRESSANTS AND THERAPEUTIC MACROMOLECULES AT A REDUCED PHARMACODYNAMICALLY EFFECTIVE DOSE SERPINA6, FCGRT, FCGR3B PPM1B 924/4885PPP2CA 882/4885PTPN1 326/4885
US-11235057-B2 Methods for providing polymeric synthetic nanocarriers for generating antigen-specific tolerance immune responses CD47, LY96, CD74 PPM1B 2644/4885PPP2CA 408/4885PTPN1 146/4885
US-11298342-B2 Methods providing a therapeutic macromolecule and synthetic nanocarriers comprising immunosuppressant locally and concomitantly to reduce both type I and type IV hypersensitivity CD74, HLA-DRB1, MSR1 PPM1B 995/4885PPP2CA 509/4885PTPN1 367/4885
US-20220354947-A1 METHODS FOR PROVIDING POLYMERIC SYNTHETIC NANOCARRIERS FOR GENERATING ANTIGEN-SPECIFIC TOLERANCE IMMUNE RESPONSES CD47, LY96, CD74 PPM1B 2644/4885PPP2CA 408/4885PTPN1 146/4885
US-20220071968-A1 METHODS OF ADMINISTERING IMMUNOSUPPRESSANTS HAVING A SPECIFIED PHARMACODYNAMIC EFFECTIVE LIFE AND THERAPEUTIC MACROMOLECULES FOR THE INDUCTION OF IMMUNE TOLERANCE IL2, CD74, HLA-DRB1 PPM1B 1513/4885PPP2CA 808/4885PTPN1 433/4885
US-12508249-B2 Methods related to administering immunosuppressants and non-allergenic antigens to reduce or prevent anaphylaxis HLA-C, CPA3, HLA-A PPM1B 3087/4885PPP2CA 2397/4885PTPN1 272/4885
US-12472167-B2 Methods providing a therapeutic macromolecule and synthetic nanocarriers comprising immunosuppressant locally and concomitantly to reduce both Type 1 and Type IV hypersensitivity CD74, CCR1, MSR1 PPM1B 622/4885PPP2CA 635/4885PTPN1 230/4885
US-20220323607-A1 SYNTHETIC NANOCARRIERS COMPRISING AN IMMUNOSUPPRESSANT IN COMBINATION WITH HIGH AFFINITY IL-2 RECEPTOR AGONISTS TO ENHANCE IMMUNE TOLERANCE IL2, IL2RA, ICOS PPM1B 2829/4885PPP2CA 547/4885PTPN1 186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.