Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.42 |
| ▸ | DRD3 | P35462 | 9/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6619493 | 0.86 | DRD2 (0.46) | DRD2DRD3HTR1DDRD4 | |
| SCHEMBL3387814 | 0.83 | DRD2 (0.42) | DRD2DRD3HTR1DDRD4 | |
| SCHEMBL6619115 | 0.81 | DRD2 (0.48) | DRD2DRD3HTR1DDRD4 | |
| SCHEMBL3390894 | 0.75 | MAPT (0.36) | DRD2DRD3DRD4 | |
| SCHEMBL6638006 | 0.75 | DRD2 (0.41) | DRD2DRD3HTR1DDRD4 | |
| SCHEMBL3390524 | 0.75 | DRD2 (0.43) | DRD2DRD3HTR1DDRD4 | |
| SCHEMBL3390359 | 0.74 | DRD2 (0.53) | DRD2DRD3HTR1DDRD4 | |
| SCHEMBL6620561 | 0.72 | MAPT (0.34) | DRD2DRD3DRD4 | |
| SCHEMBL6345233 | 0.69 | DRD2 (0.57) | DRD2DRD3DRD4 | |
| SCHEMBL6335385 | 0.69 | DRD2 (0.57) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453805-B1 | 4-PIPERIDINYL ALKYLAMINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2010-12-22 | — | — | EP | claimed |
| EP-1453805-B1 | 4-PIPERIDINYL ALKYLAMINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2010-12-22 | — | — | EP | disclosed |
| EP-1453805-A1 | 4-PIPERIDINYL ALKYLAMINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003048124-A1 | 4-PIPERIDINYL ALKYLAMINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-12 | — | — | WO | disclosed |