Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.57 |
| ▸ | DRD3 | P35462 | 15/20 | 0.57 |
| ▸ | DRD4 | P21917 | 6/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6335385 | 1.00 | DRD2 (0.57) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL6344096 | 0.96 | DRD3 (0.57) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL6336496 | 0.91 | DRD3 (0.46) | DRD2DRD3DRD4HTR1AMEN1 | |
| SCHEMBL6334415 | 0.88 | ALDH1A1 (0.44) | DRD2DRD3DRD4CYP2D6 | |
| SCHEMBL6334431 | 0.88 | DRD2 (0.53) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL6619115 | 0.88 | DRD2 (0.48) | DRD2DRD3DRD4 | |
| SCHEMBL6346804 | 0.88 | DRD3 (0.56) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL6337081 | 0.87 | DRD3 (0.40) | DRD2DRD3DRD4HTR1AMEN1 | |
| SCHEMBL3390091 | 0.87 | DRD3 (0.42) | DRD2DRD3DRD4HTR1AMEN1 | |
| SCHEMBL6345257 | 0.86 | DRD3 (0.41) | DRD2DRD3DRD4HTR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864266-B2 | 4-piperidinyl alkyl amine derivatives as muscarinic receptor antagonists | SYNTEX (U.S.A.) LLC (US) | 2005-03-08 | — | — | US | claimed |