Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4263578 | 0.90 | DPP4 (0.47) | DPP4PDE10AP2RX7 | |
| SCHEMBL1261938 | 0.86 | PDE10A (0.51) | DPP4PDE10APRKCI | |
| SCHEMBL4264217 | 0.85 | DPP4 (0.44) | DPP4PDE10AP2RX7TRPV1 | |
| SCHEMBL4274904 | 0.83 | DPP4 (0.42) | DPP4P2RX7TRPV1 | |
| SCHEMBL4275667 | 0.81 | DPP4 (0.57) | DPP4TRPV1 | |
| SCHEMBL27042576 | 0.79 | DPP4 (0.44) | DPP4P2RX7 | |
| SCHEMBL4274835 | 0.78 | DPP4 (0.51) | DPP4P2RX7 | |
| SCHEMBL4265468 | 0.78 | DPP4 (0.57) | DPP4P2RX7TRPV1 | |
| SCHEMBL1261353 | 0.78 | MTOR (0.49) | DPP4PDE10AP2RX7PRKCI | |
| SCHEMBL4266981 | 0.77 | P2RX7 (0.45) | DPP4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863812-B1 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD (KR) | 2010-07-14 | — | — | EP | disclosed |