Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390793 | 0.90 | DPP4 (0.56) | DPP4P2RX7PDE10A | |
| SCHEMBL1261353 | 0.87 | MTOR (0.49) | DPP4P2RX7PDE10AMTOR | |
| SCHEMBL4264217 | 0.85 | DPP4 (0.44) | DPP4P2RX7PDE10A | |
| SCHEMBL4274904 | 0.85 | DPP4 (0.42) | DPP4P2RX7 | |
| SCHEMBL4265468 | 0.82 | DPP4 (0.57) | DPP4P2RX7SMN1; SMN2HSD17B10 | |
| SCHEMBL4275667 | 0.82 | DPP4 (0.57) | DPP4 | |
| SCHEMBL27007528 | 0.81 | P2RX7 (0.46) | P2RX7PDE10AMTOR | |
| SCHEMBL4274835 | 0.80 | DPP4 (0.51) | DPP4P2RX7 | |
| SCHEMBL4266981 | 0.79 | P2RX7 (0.45) | DPP4P2RX7 | |
| SCHEMBL4270216 | 0.79 | DPP4 (0.39) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863812-A4 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD (KR) | 2009-06-24 | — | — | EP | disclosed |
| EP-1863812-A1 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG Life Sciences Ltd. (KR) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006104356-A1 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES, LTD. (KR) | 2006-10-05 | — | — | WO | disclosed |